Evidence map›Paper›PMID 25121090›Full record

ReviewBioMed research international2014

New acquisition protocol of 18F-choline PET/CT in prostate cancer patients: review of the literature about methodology and proposal of standardization.

Sotirios Chondrogiannis, Maria Cristina Marzola, Gaia Grassetto, Anna Margherita Maffione, Lucia Rampin, Emma Veronese, Arianna Massaro, Domenico Rubello

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 31 citations in OpenAlex.

  1. Diagnostic accuracy ofFrontiers in medicine · 2026
    Article
  2. Multitracer PET/CT with [Diagnostics (Basel, Switzerland) · 2023
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sotirios ChondrogiannisDepartment of Nuclear Medicine, PET/CT Centre, "Santa Maria della Misericordia" Hospital, Via Tre Martiri 140, 45100 Rovigo, Italy.
Maria Cristina MarzolaDepartment of Nuclear Medicine, PET/CT Centre, "Santa Maria della Misericordia" Hospital, Via Tre Martiri 140, 45100 Rovigo, Italy.
Gaia GrassettoDepartment of Nuclear Medicine, PET/CT Centre, "Santa Maria della Misericordia" Hospital, Via Tre Martiri 140, 45100 Rovigo, Italy.
Anna Margherita MaffioneDepartment of Nuclear Medicine, PET/CT Centre, "Santa Maria della Misericordia" Hospital, Via Tre Martiri 140, 45100 Rovigo, Italy.
Lucia RampinDepartment of Nuclear Medicine, PET/CT Centre, "Santa Maria della Misericordia" Hospital, Via Tre Martiri 140, 45100 Rovigo, Italy.
Emma VeroneseDepartment of Nuclear Medicine, PET/CT Centre, "Santa Maria della Misericordia" Hospital, Via Tre Martiri 140, 45100 Rovigo, Italy.
Arianna MassaroDepartment of Nuclear Medicine, PET/CT Centre, "Santa Maria della Misericordia" Hospital, Via Tre Martiri 140, 45100 Rovigo, Italy.
Domenico RubelloDepartment of Nuclear Medicine, PET/CT Centre, "Santa Maria della Misericordia" Hospital, Via Tre Martiri 140, 45100 Rovigo, Italy.
Ospedale Santa Maria della Misericordia di Rovigo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose(1) To evaluate a new acquisition protocol of (18)F-choline (FCH) PET/CT for prostate cancer patients (PC), (2) to review acquisition (18)F-choline PET/CT methodology, and (3) to propose a standardized acquisition protocol on FCH PET/CT in PC patients. MATERIALS: 100 consecutive PC patients (mean age 70.5 years, mean PSA 21.35 ng/mL) were prospectively evaluated. New protocol consisted of an early scan of the pelvis immediately after the injection of the tracer (1 bed position of 4 min) followed by a whole body scan at one 1 hour. Early and 1 hour images were compared for interfering activity and pathologic findings.

resultsThe overall detection rate of FCH PET/CT was 64%. The early static images of the pelvis showed absence of radioactive urine in ureters, bladder, or urethra which allowed a clean evaluation of the prostatic fossae. Uptake in the prostatic region was better visualized in the early phase in 26% (7/30) of cases. Other pelvic pathologic findings (bone and lymph nodes) were visualized in both early and late images.

conclusionEarly (18)F-choline images improve visualization of abnormal uptake in prostate fossae. All pathologic pelvic deposits (prostate, lymph nodes, and bone) were visualized in both early and late images.

Indexed as

AdultAgedAged, 80 and overCholineHumansLymph NodesMaleMiddle AgedPositron-Emission TomographyProstatic NeoplasmsRecurrenceReference StandardsTomography, X-Ray ComputedCholinefluoromethylcholine

Identifiers

PMID25121090
PMCPMC4119889
OpenAlexW2092583568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.