Evidence map›Paper›PMID 25121083›Full record

ArticleFrontiers in public health2014

Discharge β-Blocker Use and Race after Coronary Artery Bypass Grafting.

Wesley T O'Neal, Jimmy T Efird, Stephen W Davies, Jason B O'Neal, William F Griffin, T Bruce Ferguson, W Randolph Chitwood, Alan P Kypson

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Wesley T O'NealDepartment of Internal Medicine, Wake Forest School of Medicine , Winston-Salem, NC , USA.
Jimmy T EfirdEast Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University , Greenville, NC , USA ; Center for Health Disparities, Brody School of Medicine, East Carolina University , Greenville, NC , USA.
Stephen W DaviesDepartment of General Surgery, University of Virginia School of Medicine , Charlottesville, VA , USA.
Jason B O'NealDepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA , USA.
William F GriffinEast Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University , Greenville, NC , USA.
T Bruce FergusonEast Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University , Greenville, NC , USA.
W Randolph ChitwoodEast Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University , Greenville, NC , USA.
Alan P KypsonEast Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University , Greenville, NC , USA.
East Carolina University · USHarvard University · USUniversity of Virginia · USWake Forest University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe use of discharge β-blockers after cardiac surgery is associated with a long-term mortality benefit. β-Blockers have been suggested to be less effective in black cardiovascular patients compared with whites. To date, racial differences in the long-term survival of coronary artery bypass grafting (CABG) patients who receive β-blockers at discharge have not been examined.

methodsA retrospective cohort study was conducted on patients undergoing CABG between 2002 and 2011. Long-term survival was compared in patients who were and who were not discharged with β-blockers. Hazard ratios (HR) and 95% confidence intervals (CI) were computed using a Cox regression model. P-for-interaction between race and discharge β-blocker use was computed using a likelihood ratio test.

resultsA total of 853 (88%) black (n = 970) and 3,038 (88%) white (n = 3,460) patients had a history of β-blocker use at discharge (N = 4,430). Black patients who received β-blockers survived longer than those not receiving β-blockers and the survival advantage was comparable with white patients (black, adjusted HR = 0.33, 95% CI = 0.23-0.46; white, adjusted HR = 0.48, 95% CI = 0.39-0.58; p-for-interaction = 0.74). Among patients discharged on β-blockers, we did not observe a long-term survival advantage for white compared with black patients (HR = 1.2, 95% CI = 0.95-1.5).

conclusionβ-Blocker use at discharge was associated with a survival advantage among black patients after CABG and a similar association was observed in white patients.

Indexed as

CABGcardiologyepidemiologyoutcomesβ-blockers

Identifiers

PMID25121083
PMCPMC4114325
OpenAlexW2144471791

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.