ReviewFrontiers in public health2014
Delay in breast cancer: implications for stage at diagnosis and survival.
Review in Frontiers in public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 8 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
136 citing papers in PubMed, 8 syntheses or guidelines pooled it, 268 citations in OpenAlex.
- Utility of CA-125 for diagnosis and prognosis of breast cancer: a systematic review.Exploration of targeted anti-tumor therapy · 2025Pooled it
- Advanced-stage breast cancer diagnosis and its determinants in Ethiopia: a systematic review and meta-analysis.BMC women's health · 2024Pooled it
- A systematic review of the impact of the COVID-19 pandemic on breast cancer screening and diagnosis.Breast (Edinburgh, Scotland) · 2023Pooled it
- Cultural, Religious and Socio-Ethical Misconceptions among Muslim Women towards Breast Cancer Screening: A Systematic Review.Asian Pacific journal of cancer prevention : APJCP · 2022Pooled it
- ESMO Management and treatment adapted recommendations in the COVID-19 era: Breast Cancer.ESMO open · 2020Guideline
- Pooled it
- Timely follow-up of positive cancer screening results: A systematic review and recommendations from the PROSPR Consortium.CA: a cancer journal for clinicians · 2018Pooled it
- Association between MGMT Promoter Methylation and Risk of Breast and Gynecologic Cancers: A Systematic Review and Meta-Analysis.Scientific reports · 2017Pooled it
- Trial
- Assessment and model guided cancer screening promotion by village doctors in China: a randomized controlled trial protocol.BMC cancer · 2015Trial
- Impact of and recovery after Covid-19 on breast cancer diagnosis and care in Johannesburg, South Africa.BMC cancer · 2026Article
- Digital Breast Tomosynthesis Use, Facility Mammography Volume, and Timely Follow-Up After Abnormal Screening Mammograms in Appalachia, United States.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2026Article
- Factors Associated With Delay in Seeking Medical Care Among Breast Cancer Patients in Bangladesh.Cureus · 2026Article
- Psychological consequences of mammography screening recommendations: a prospective cohort study in Iran.BMC psychology · 2026Article
- Understanding Delays in Breast Cancer Diagnosis in Bangladesh: A Facility-Based Cross-Sectional Study.Health science reports · 2026Article
- The combination of rosuvastatin and meloxicam enhances the radiotherapy efficacy of MCF7, T-47D, and MDA-MB-231 breast cancer cell lines.Research in pharmaceutical sciences · 2026Article
- Agreement Among Breast Cancer Screening Modalities in Breast Density Assessment and Cancer Risk Prediction.International journal of breast cancer · 2026Article
- Article
- Subtype-specific health and economic impact of delayed breast cancer diagnosis during the early COVID-19 pandemic in Belgium: a Markov model analysis.Breast cancer research : BCR · 2025Article
- Factors associated with late diagnosis of breast cancer among women in Botswana.African journal of primary health care & family medicine · 2025Article
76 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer continues to be a disease with tremendous public health significance. Primary prevention of breast cancer is still not available, so efforts to promote early detection continue to be the major focus in fighting breast cancer. Since early detection is associated with decreased mortality, one would think that it is important to minimize delays in detection and diagnosis. There are two major types of delay. Patient delay is delay in seeking medical attention after self-discovering a potential breast cancer symptom. System delay is delay within the health care system in getting appointments, scheduling diagnostic tests, receiving a definitive diagnosis, and initiating therapy. Earlier studies of the consequences of delay on prognosis tended to show that increased delay is associated with more advanced stage cancers at diagnosis, thus resulting in poorer chances for survival. More recent studies have had mixed results, with some studies showing increased survival with longer delays. One hypothesis is that diagnostic difficulties could perhaps account for this survival paradox. A rapidly growing lump may suggest cancer to both doctors and patients, while a slow growing lump or other symptoms could be less obvious to them. If this is the case, then the shorter delays would be seen with the more aggressive tumors for which the prognosis is worse leading to reduced survival. It seems logical that a tumor that is more advanced at diagnosis would lead to shorter survival but the several counter-intuitive studies in this review show that it is dangerous to make assumptions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.