ReviewFrontiers in physiology2014
Sympathetic dysfunction in vasovagal syncope and the postural orthostatic tachycardia syndrome.
Review in Frontiers in physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Alterations of Attention in Patients With Postural Tachycardia Syndrome and Healthy Controls Depending on Body Position and Hydration
Muscular and Cutaneous Dysfunction in Postural Tachycardia Syndrome
Who cites it
24 citing papers in PubMed, 56 citations in OpenAlex.
- Orthostatic blood pressure changes among adults in Ekiti state, Nigeria: Impact of socio-demographic, anthropometric, and biophysical factors.Physiological reports · 2026Article
- Changes in Autonomic Balance, Cardiac Parasympathetic Modulation, and Cardiac Baroreflex Gain in Older Adults Under Different Orthostatic Stress Conditions.Healthcare (Basel, Switzerland) · 2025Article
- Comparative analysis of autonomic nervous system function in patients with postural orthostatic tachycardia syndrome versus a head-up tilt testing-negative cohort.IBRO neuroscience reports · 2025Article
- Effects of different postures on the hemodynamics and cardiovascular autonomic control responses to exercise in postural orthostatic tachycardia syndrome.European journal of applied physiology · 2025Article
- Visual symptoms in postural tachycardia syndrome: An investigation of position-dependent visual exploration.European journal of neurology · 2025Article
- The Head-Up Tilt Table Test as a Measure of Autonomic Functioning among Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.Journal of personalized medicine · 2024Article
- Cardiac deceleration capacity and acceleration capacity have diagnostic value in patients with vasovagal syncope regardless of age.Frontiers in cardiovascular medicine · 2024Article
- Comparisons of heart rate variability responses to head-up tilt with and without abdominal and lower-extremity compression in healthy young individuals: a randomized crossover study.Frontiers in physiology · 2023Article
- Evaluation of electrocardiographic parameters in amputee football players.Frontiers in psychology · 2023Article
- Use of Multimodal Therapies to Treat Severe Orthostatic Hypotension From Autonomic Failure.Cureus · 2022Article
- Orthostatic intolerance and neurocognitive impairment in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).Epidemiologic methods · 2022Article
- Gravity Threshold and Dose Response Relationships: Health Benefits Using a Short Arm Human Centrifuge.Frontiers in physiology · 2021Article
- Article
- Sodium glucose co-transporter 2 inhibition reduces succinate levels in diabetic mice.World journal of gastroenterology · 2020Article
- The tilt table test is useful for the diagnosis of vasovagal syncope and should not be abolished.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Relationship between Ischemic Stroke and Pulse Rate Variability as a Surrogate of Heart Rate Variability.Brain sciences · 2019Article
- Vagal and Sympathetic Function in Neuropathic Postural Tachycardia Syndrome.Hypertension (Dallas, Tex. : 1979) · 2019Article
- Article
- Orthostatic Cognitive Dysfunction in Postural Tachycardia Syndrome After Rapid Water Drinking.Frontiers in neuroscience · 2019Article
- Sleep Fainting: A Neurocardiogenic Entity.Cureus · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orthostatic intolerance is the inability to tolerate the upright posture and is relieved by recumbence. It most commonly affects young women and has a major impact on quality of life and psychosocial well-being. Several forms of orthostatic intolerance have been described. The most common one is the recurrent vasovagal syncope (VVS) phenotype which presents as a transient and abrupt loss of consciousness and postural tone that is followed by rapid recovery. Another common type of orthostatic intolerance is the postural orthostatic tachycardia syndrome (POTS) which is characterized by an excessive rise in heart rate upon standing and is associated with symptoms of presyncope such as light-headedness, fatigue, palpitations, and nausea. Maintenance of arterial pressure under condition of reduced central blood volume during the orthostasis is accomplished in large part through sympathetic efferent nerve traffic to the peripheral vasculature. Therefore sympathetic nervous system (SNS) dysfunction is high on the list of possible contributors to the pathophysiology of orthostatic intolerance. Investigations into the role of the SNS in orthostatic intolerance have yielded mixed results. This review outlines the current knowledge of the function of the SNS in both VVS and POTS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.