ArticleEuropean radiology2014
Anatomic variants of the pancreatic duct and their clinical relevance: an MR-guided study in the general population.
Article in European radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 100 citations in OpenAlex.
- The Prevalence of Pancreas Divisum and Its Association with Pancreatic Diseases: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Causal Evaluation of Acute Recurrent and Chronic Pancreatitis in Children: Consensus From the INSPPIRE Group.Journal of pediatric gastroenterology and nutrition · 2017Pooled it
- Incidence and clinical significance of biliary and pancreatic duct variations on magnetic resonance cholangiopancreatography.Abdominal radiology (New York) · 2026Article
- Breaking Through the Barrier: Nanoparticle-Driven MRI Strategies for Diagnosis and Therapy of Pancreatic Cancer.ACS nanoscience Au · 2026Review
- The Role of Endoscopic Ultrasound in the Diagnosis and Management of Congenital Gastrointestinal and Pancreaticobiliary Conditions.Current gastroenterology reports · 2026Review
- Article
- Prospective study on outcomes of endotherapy for pancreatic divisum in patients of recurrent acute pancreatitis.Endoscopy international open · 2025Article
- Choledochal Cyst and Pancreas Divisum: A Case Report.The American journal of case reports · 2024Article
- Exploring the variations of the pancreatic ductal system: a systematic review and meta-analysis of observational studies.Anatomy & cell biology · 2024Article
- Classification of anatomical morphology of cystic duct and its association with gallstone.World journal of gastrointestinal surgery · 2024Article
- PANCREATODUODENECTOMY AS TREATMENT FOR RECURRENT ACUTE PANCREATITIS DUE TO PANCREAS DIVISUM.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2024Article
- Article
- EUS-guided rendezvous technique for pancreas divisum.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2023Article
- Anatomical pancreatic variants in intraductal papillary mucinous neoplasm patients: a cross-sectional study.BMC gastroenterology · 2022Article
- SHIP-MR and Radiology: 12 Years of Whole-Body Magnetic Resonance Imaging in a Single Center.Healthcare (Basel, Switzerland) · 2021Review
- A New Quantitative Classification of the Extrahepatic Biliary Tract Related to Cystic Duct Implantation.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Article
- Clinical outcome of endoscopic therapy in patients with symptomatic pancreas divisum: a Dutch cohort study.Endoscopy international open · 2021Article
- Proximal Migration of Pancreatic Duct Stent in Pancreas Divisum: Challenges in Retrieval and Review of the Literature.Case reports in gastrointestinal medicine · 2021Article
- Pancreatic senescence and its clinical manifestations.Aging medicine (Milton (N.S.W)) · 2020Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the frequency of pancreatic duct (PD) variants and their effect on pancreatic exocrine function in a population-based study using non-invasive secretin-stimulated magnetic resonance cholangiopancreatography (sMRCP).
methodsNine hundred and ninety-five volunteers, 457 women and 538 men, aged 51.9 ± 13.4 years, underwent navigator-triggered, T2-weighted, 3D turbo spin echo MRCP on a 1.5 T system after 1 unit/kg secretin administration. Two readers evaluated images for PD variants. Pancreatic exocrine function and morphological signs of chronic pancreatitis such as abnormalities of the main PD, side branch dilatation, and pancreatic cysts were evaluated and related to PD variants using a Kruskal-Wallis test and post hoc analysis.
resultsOf all sMRCP, 93.2% were of diagnostic quality. Interobserver reliability for detection of PD variants was found to be kappa 0.752 (95 %CI, 0.733 - 0.771). Normal PD variants were observed in 90.4% (n = 838/927). Variants of pancreas divisum was identified in 9.6% (n = 89/927). Abnormalities of the main PD, side branch dilatation, and pancreatic cysts were observed in 2.4%, 16.6%, and 27.7%, respectively, and were not significantly different between pancreas divisum and non-divisum group (P = 0.122; P = 0.152; P = 0.741). There was no association between PD variants and pancreatic exocrine function (P = 0.367).
conclusionPD variants including pancreas divisum are not associated with morphological signs of chronic pancreatitis or restriction of pancreatic exocrine function. KEY POINTS: MRCP allows the evaluation of pancreatic duct variants and morphological change. Pancreatic duct variants are not associated with morphological signs of chronic pancreatitis. Pancreas divisum is not accompanied by restriction of pancreatic exocrine function. Pancreatic duct variants including pancreas divisum are limited in their clinical relevance.
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