Evidence map›Paper›PMID 25120184›Full record

ArticleAnalytical and bioanalytical chemistry2015

Emerging trends in precision fabrication of microapertures to support suspended lipid membranes for sensors, sequencing, and beyond.

Christopher A Baker, Craig A Aspinwall

Open access · greenAbstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Bioinspired Assemblies and Plasmonic Interfaces for Electrochemical Biosensing.Journal of electroanalytical chemistry (Lausanne, Switzerland) · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Christopher A BakerDepartment of Chemistry and Biochemistry, University of Arizona, 1306 E. University Blvd, Tucson, AZ, 85721, USA.
Craig A Aspinwall
University of Arizona · US

Funding

Sniffer Biosensors Based on Ion Channel-GPCR Chimeras and Polylipid MembranesR01EB007047 · NIBIB · UNIVERSITY OF ARIZONA · PI ASPINWALL, CRAIG A, SAAVEDRA, STEVEN SCOTT · 2006 to 2015
$3.5M
Stabilized Biomimetic Separation MediaR01GM095763 · NIGMS · UNIVERSITY OF ARIZONA · PI ASPINWALL, CRAIG A · 2011 to 2014
$1.1M
NIBIB NIH HHS EB007047NIBIB NIH HHS R01 EB007047NIGMS NIH HHS GM095763NIGMS NIH HHS R01 GM095763
6 · The paper itself

Abstract

Suspended lipid membranes, also called black lipid membranes (BLMs), are an important model system that approximates the lipid bilayer environment of cell membranes. Increasingly, BLMs are utilized in sensing strategies that harness high sensitivity measurements of ion flux across the membrane, typically facilitated by ion channel proteins. BLMs are suspended across microapertures that connect two otherwise isolated fluidic compartments, and the precision fabrication of such microapertures can contribute to the stability and performance of the resulting BLM. Here, we highlight two emerging trends in the precision fabrication of microapertures for BLM formation: microfabrication in silicon-based thin film substrates, and microfabrication in the negative photoresist material SU-8. Four unique fabrication strategies are outlined, and we project the impact that these microfabrication strategies will have for BLM-integrated bioanalytical technologies.

Indexed as

Lipid BilayersBiochemistryEpoxy CompoundsEquipment DesignMembrane LipidsMicrotechnologyPolymersSiliconEpoxy CompoundsLipid BilayersMembrane LipidsPolymersSiliconSU-8 compound

Identifiers

PMID25120184
PMCPMC4305479
OpenAlexW1995761840

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.