Evidence map›Paper›PMID 25120157›Full record

ArticleSensors (Basel, Switzerland)2014

Development of a PET scanner for simultaneously imaging small animals with MRI and PET.

Christopher J Thompson, Andrew L Goertzen, Jonathan D Thiessen, Daryl Bishop, Greg Stortz, Piotr Kozlowski, Fabrice Retière, Xuezhu Zhang, Vesna Sossi

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Advances in PET/MR instrumentation and image reconstruction.The British journal of radiology · 2018
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christopher J ThompsonMontreal Neurological Institute, McGill University, 11870 Lavigne, Montreal, QC H4J1X8, Canada. Christopher.Thompson@McGill.Ca.
Andrew L GoertzenDepartment of Radiology, University of Manitoba, 807L-715 McDermot Ave. Winnipeg, MB R3E 3P4, Canada. xuezhu.zhang@hotmail.com.
Jonathan D ThiessenImaging Program, Lawson Health Research Institute, 800 Commissioners Road East, London, ON N6A 5W9, Canada. jthiessen@lawsonimaging.ca.
Daryl BishopDetector Development Group, TRIUMF, 4004 Westbrook Mall, Vancouver, BC V6T 2A3, Canada. daryl@triumf.ca.
Greg StortzDepartment of Physics and Astronomy, University of British Columbia, 2350 Health Sciences Mall, B3711 Vancouver, BC V6T 1Z3, Canada. gregstortz@gmail.com.
Piotr KozlowskiDepartment of Radiology, University of British Columbia, 2350 Health Sciences Mall, B3711 Vancouver, BC V6T 1Z3, Canada. Piotr.Kozlowski@ubc.ca.
Fabrice RetièreDetector Development Group, TRIUMF, 4004 Westbrook Mall, Vancouver, BC V6T 2A3, Canada. fretiere@triumf.ca.
Xuezhu ZhangDepartment of Physics and Astronomy, University of Manitoba, Winnipeg, MB R3E 3P4, Canada. xuezhu.zhang@hotmail.com.
Vesna SossiDepartment of Physics and Astronomy, University of British Columbia, 2350 Health Sciences Mall, B3711 Vancouver, BC V6T 1Z3, Canada. vesna@phas.ubc.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, positron emission tomography (PET) is playing an increasingly important role in the diagnosis and staging of cancer. Combined PET and X-ray computed tomography (PET-CT) scanners are now the modality of choice in cancer treatment planning. More recently, the combination of PET and magnetic resonance imaging (MRI) is being explored in many sites. Combining PET and MRI has presented many challenges since the photo-multiplier tubes (PMT) in PET do not function in high magnetic fields, and conventional PET detectors distort MRI images. Solid state light sensors like avalanche photo-diodes (APDs) and more recently silicon photo-multipliers (SiPMs) are much less sensitive to magnetic fields thus easing the compatibility issues. This paper presents the results of a group of Canadian scientists who are developing a PET detector ring which fits inside a high field small animal MRI scanner with the goal of providing simultaneous PET and MRI images of small rodents used in pre-clinical medical research. We discuss the evolution of both the crystal blocks (which detect annihilation photons from positron decay) and the SiPM array performance in the last four years which together combine to deliver significant system performance in terms of speed, energy and timing resolution.

Indexed as

AnimalsDiagnostic ImagingEquipment DesignMagnetic Resonance ImagingPhotonsPositron-Emission TomographySiliconTomography, X-Ray ComputedSilicon

Identifiers

PMID25120157
PMCPMC4178985

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.