Evidence map›Paper›PMID 25120144›Full record

ArticleThe Journal of investigative dermatology2014

Proteomic revelations.

Jeffrey M Davidson

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jeffrey M DavidsonDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA; Research Service, VA Tennessee Valley Healthcare System, Nashville, Tennessee, USA. Electronic address: jeff.davidson@vanderbilt.edu.
Vanderbilt University · US

Funding

Skin Regeneration with Stem Cells and ScaffoldsR01AR056138 · NIAMS · VANDERBILT UNIVERSITY · PI DAVIDSON, JEFFREY M., GUELCHER, SCOTT A · 2009 to 2013
$3.3M
NIAMS NIH HHS AR056138NIAMS NIH HHS R01 AR056138
6 · The paper itself

Abstract

The power of proteomics in cultured skin fibroblasts from individuals with either systemic sclerosis or recessive dystrophic epidermolysis bullosa has led to the common finding of senescence and deficiencies in autophagy. Both of these disorders exert high demand on fibroblast activity, and without the protective action of autophagy cellular stress could have many adverse effects that are further amplified by the senescent phenotype.

Indexed as

Epidermolysis Bullosa DystrophicaAutophagyCollagen Type VIIDermisEpidermisFemaleGTP-Binding ProteinsHumansMaleMinichromosome Maintenance Complex Component 7Protein Glutamine gamma Glutamyltransferase 2Scleroderma, SystemicSkin AgingTransglutaminasesCOL7A1 protein, humanCollagen Type VIIGTP-Binding ProteinsMCM7 protein, humanMinichromosome Maintenance Complex Component 7Protein Glutamine gamma Glutamyltransferase 2Transglutaminases

Identifiers

PMID25120144
PMCPMC4133747
OpenAlexW4235342643

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.