Evidence map›Paper›PMID 25119757›Full record

ArticleRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2014

Cardiac autonomic dysfunction in obese normotensive children and adolescents.

Isabelle Magalhães G Freitas, Josiane Aparecida Miranda, Pedro Augusto C Mira, Carla Marcia M Lanna, Jorge Roberto P Lima, Mateus Camaroti Laterza

Open access · diamondAbstract read
In one paragraph

Article in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Cardiac autonomic dysfunction in children and adolescents with obesity: a systematic review and meta-analysis.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2026
    Pooled it
  2. Trial
  3. Review
  4. Adiposity and cardiac autonomic function in children with a family history of obesity.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Observational
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Isabelle Magalhães G FreitasUFJF, Juiz de Fora, MG, Brasil.
Josiane Aparecida MirandaUFJF, Juiz de Fora, MG, Brasil.
Pedro Augusto C MiraUFJF, Juiz de Fora, MG, Brasil.
Carla Marcia M LannaUFJF, Juiz de Fora, MG, Brasil.
Jorge Roberto P LimaUFJF, Juiz de Fora, MG, Brasil.
Mateus Camaroti LaterzaUFJF, Juiz de Fora, MG, Brasil.
Universidade Federal de Juiz de Fora · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo test the hypothesis that obese normotensive children and adolescents present impaired cardiac autonomic control compared to non-obese normotensive ones.

methodsFor this cross-sectional study, 66 children and adolescents were divided into the following groups: Obese (n=31, 12±3 years old) and Non-Obese (n=35, 13±3 years old). Obesity was defined as body mass index greater than the 95th percentile for age and gender. Blood pressure was measured by oscillometric method after 15 minutes of rest in supine position. The heart rate was continuously registered during ten minutes in the supine position with spontaneous breathing. The cardiac autonomic control was assessed by heart rate variability, which was calculated from the five-minute minor variance of the signal. The derivations were the index that indicates the proportion of the number of times in which normal adjacent R-R intervals present differences >50 miliseconds (pNN50), for the time domain, and, for the spectral analysis, low (LF) and high frequency (HF) bands, besides the low and high frequencies ratio (LF/HF). The results were expressed as mean±standard deviation and compared by Student's t-test or Mann-Whitney's U-test.

resultsSystolic blood pressure (116±14 versus 114±13mmHg, p=0.693) and diastolic blood pressure (59±8 versus 60±11mmHg, p=0.458) were similar between the Obese and Non-Obese groups. The pNN50 index (29±21 versus 43±23, p=0.015) and HF band (54±20 versus 64±14 normalized units - n.u., p=0.023) were lower in the Obese Group. The LF band (46±20 versus 36±14 n.u., p=0.023) and LF/HF ratio (1.3±1.6 versus 0.7±0.4, p=0.044) were higher in Obese Group.

conclusionsObese normotensive children and adolescents present impairment of cardiac autonomic control.

Indexed as

AdolescentAutonomic Nervous SystemBlood PressureChildCross-Sectional StudiesFemaleHeartHumansMalePediatric ObesityReference Values

Identifiers

PMID25119757
PMCPMC4183014
OpenAlexW1995365587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.