ReviewOrganic & biomolecular chemistry2014
Nitroso Diels-Alder (NDA) reaction as an efficient tool for the functionalization of diene-containing natural products.
Review in Organic & biomolecular chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- One-Step Photoreduction of Nitroarenes to Nitrosoarenes.Organic letters · 2026Article
- Copper-Catalyzed Three-Component Selective 1,4-Amino Oxygenation of 1,3-Dienes.Angewandte Chemie (International ed. in English) · 2026Article
- Disulfide-Containing Nitrosoarenes: Synthesis and Insights into Their Self-Polymerization on a Gold Surface.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Recent advances in total synthesis of illisimonin A.Beilstein journal of organic chemistry · 2025Review
- Copper-Catalyzed 1,4-Aminohydroxylation and Aminothiolation of 1,3-Dienes by Carbonyl-Assisted Migration.Chem catalysis · 2024Article
- Valence-isomer selective cycloaddition reaction of cycloheptatrienes-norcaradienes.Nature communications · 2024Article
- The Development and Mechanistic Study of an Iron-Catalyzed Intramolecular Nitroso Ene Reaction of Nitroarenes.ACS catalysis · 2023Article
- Development of New Reactions Driven by N-O Bond Cleavage: fromSynlett : accounts and rapid communications in synthetic organic chemistry · 2023Article
- α-Diimine synthesisChemical science · 2022Article
- Alternating Current Electrolysis as Efficient Tool for the Direct Electrochemical Oxidation of Hydroxamic Acids for Acyl Nitroso Diels-Alder Reactions.Angewandte Chemie (International ed. in English) · 2021Article
- Davis-Beirut Reaction Inspired Nitroso Diels-Alder Reaction.Tetrahedron letters · 2021Article
- Nitroso Diels-Alder Cycloadducts Derived FromMolecules (Basel, Switzerland) · 2020Review
- Direct introduction of nitrogen and oxygen functionality with spatial control using copper catalysis.Chemical science · 2018Article
- Applications of Nonenzymatic Catalysts to the Alteration of Natural Products.Chemical reviews · 2017Review
- A new sensitive LC/MS/MS analysis of vitamin D metabolites using a click derivatization reagent, 2-nitrosopyridine.Journal of lipid research · 2017Article
- Stereo- and regioselectivity of the hetero-Diels-Alder reaction of nitroso derivatives with conjugated dienes.Beilstein journal of organic chemistry · 2016Review
- Continuous flow of nitroso Diels-Alder reaction.Chemical communications (Cambridge, England) · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
This review describes the use of nitroso Diels-Alder reactions for the functionalization of complex diene-containing natural products in order to generate libraries of compounds with potential biological activity. The application of this methodology to the structural modification of a series of natural products (thebaine, steroidal dienes, rapamycin, leucomycin, colchicine, isocolchicine and piperine) is discussed using relevant examples from the literature from 1973 onwards. The biological activity of the resulting compounds is also discussed. Additional comments are provided that evaluate the methodology as a useful tool in organic, bioorganic and medicinal chemistry.
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Registered trials
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