Evidence map›Paper›PMID 25119343›Full record

ArticleDer Nervenarzt2014

[Generalized anxiety disorder].

J Plag, S Schumacher, A Ströhle

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Der Nervenarzt, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02662803 (Clinical, Neurophysiological and Neuroendocrine Effects of Aerobe Exercise in Generalized Anxiety Disorder), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02662803 nacompletednot on this mapstarted 2015, after this paper: background citation

Clinical, Neurophysiological and Neuroendocrine Effects of Aerobe Exercise in Generalized Anxiety Disorder (GAD)

TypeinterventionalSponsorCharite University, Berlin, GermanyRan2015 to 2019Enrolled29ConditionsGeneralized Anxiety Disorder (GAD)Armshigh-intensive aerobe exercise, low-intensive aerobe exercise
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Interconnectivity of fear of progression and generalized anxiety - Network analysis among a sample of hematological cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

J PlagKlinik für Psychiatrie und Psychotherapie , Charité - Universitätsmedizin Berlin, Campus Mitte, Charitéplatz 1, 10117, Berlin, Deutschland, jens.plag@charite.de.
S Schumacher
A Ströhle
Charité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Generalized anxiety disorder (GAD) is a prevalent mental condition with substantial impact on psychosocial functioning and quality of life. There is also an increased risk of comorbidity with several other mental and somatic diseases. Clinical symptomatology is characterized by excessive and uncontrollable worrying about distinct issues of daily living which is frequently associated with somatic symptoms of stress and anxiety. Neurobiological and psychological research provide evidence for alterations in (para) limbic areas, a disturbed monoaminergic transmission as well as for dysfunctional learning in the pathogenesis of GAD. Therefore, second generation antidepressants, such as selective serotonin reuptake inhibitors (SSRI), selective serotonin-norepinephrine reuptake inhibitors (SSNRI), the calcium channel modulator pregabalin and cognitive behavioral therapy (CBT) are the first choice treatment options. Depending on symptom severity, patient preference and availability, both medication and CBT can be applied as monotherapy or in combination.

Indexed as

Antidepressive AgentsAnxiety DisordersCognitive Behavioral TherapyCombined Modality TherapyEvidence-Based MedicineHumansTreatment OutcomeAntidepressive Agents

Identifiers

PMID25119343
OpenAlexW156890042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.