SynthesisNeuropsychology review2014
The effects of healthy aging, amnestic mild cognitive impairment, and Alzheimer's disease on recollection and familiarity: a meta-analytic review.
Synthesis in Neuropsychology review, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
112 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis of individual differences in naturalistic sleep quality and episodic memory performance in young and older adults.Neuroscience and biobehavioral reviews · 2021Pooled it
- Electroacupuncture for treating the cognitive symptoms of Alzheimer's disease: a randomized controlled trial.Frontiers in psychiatry · 2026Trial
- Are age differences in recognition-based retrieval monitoring an epiphenomenon of age differences in memory?Psychology and aging · 2021Trial
- Maintaining and regaining episodic memory in Alzheimer disease: a circuit-based perspective.Nature reviews. Neurology · 2026Review
- Breaking the nap habit: one-year nap restriction mitigates memory decline in older adults.GeroScience · 2026Article
- Towards a unified theory of false memory for similar episodes.Psychonomic bulletin & review · 2026Review
- Clinical recognition memory testing in older adults should move beyond accuracy alone.Frontiers in psychology · 2026Article
- A Scoping Review on Conversational Memory and Characteristics of Conversations in Alzheimer's Disease.Journal of speech, language, and hearing research : JSLHR · 2025Article
- The relationship between category-level neural differentiation and exploratory eye movements in healthy young and older adults.Neurobiology of aging · 2025Article
- Does sleep change the emotional bias in memory in older adults?Neuropsychologia · 2025Article
- Effects of age on the strategic control of recollected content as reflected by modulation of neural correlates of scene retrieval.Neurobiology of aging · 2025Article
- Development and interpretation of a machine learning risk prediction model for post-stroke depression in a Chinese population.Scientific reports · 2025Article
- Recognition Subtests for Form B of the Repeatable Battery for the Assessment of Neuropsychological Status: Preliminary Validation.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Observational
- Age Differences in Brain Functional Connectivity Underlying Proactive Interference in Working Memory.Human brain mapping · 2025Article
- "The Butcher on the Bus" Is Less Familiar to Older Adults Than She Is to Younger Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Uncovering atrophy progression pattern and mechanisms in individuals at risk of Alzheimer's disease.Brain communications · 2025Article
- Long-term retention of real-world experiences in a patient with profound amnesia.Neuropsychologia · 2024Article
- Deficits in memory metacognitive efficiency in late adulthood are related to distinct brain profile.Memory (Hove, England) · 2024Article
- Memory-related brain potentials for visual objects in early AD show impairment and compensatory mechanisms.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Cognitive modeling of the Mnemonic Similarity Task as a digital biomarker for Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
52 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
It is well established that healthy aging, amnestic Mild Cognitive Impairment (aMCI), and Alzheimer's Disease (AD) are associated with substantial declines in episodic memory. However, there is still debate as to how two forms of episodic memory - recollection and familiarity - are affected by healthy and pathological aging. To address this issue we conducted a meta-analytic review of the effect sizes reported in studies using remember/know (RK), receiver operating characteristic (ROC) and process dissociation (PD) methods to examine recollection and familiarity in healthy aging (25 published reports), aMCI (9 published reports), and AD (5 published reports). The results from the meta-analysis revealed that healthy aging is associated with moderate-to-large recollection impairments. Familiarity was not impaired in studies using ROC or PD methods but was impaired in studies that used the RK procedure. aMCI was associated with large decreases in recollection whereas familiarity only tended to show a decrease in studies with a patient sample comprised of both single-domain and multiple-domain aMCI patients. Lastly, AD was associated with large decreases in both recollection and familiarity. The results are consistent with neuroimaging evidence suggesting that the hippocampus is critical for recollection whereas familiarity is dependent on the integrity of the surrounding perirhinal cortex. Moreover, the results highlight the relevance of method selection when examining aging, and suggest that familiarity deficits might be a useful behavioral marker for identifying individuals that will develop dementia.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.