ArticleNeuroradiology2014
The effects of hemorrhagic parenchymal infarction on the establishment of sensori-motor structural and functional connectivity in early infancy.
Article in Neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 46 citations in OpenAlex.
- Altered functional connectivity in preterm neonates with intraventricular hemorrhage assessed using functional near-infrared spectroscopy.Scientific reports · 2024Article
- Three-dimensional cranial ultrasound and functional near-infrared spectroscopy for bedside monitoring of intraventricular hemorrhage in preterm neonates.Scientific reports · 2023Article
- Neuroimaging of structural and functional connectivity in preterm infants with intraventricular hemorrhage.Seminars in perinatology · 2022Review
- Development of functional organization within the sensorimotor network across the perinatal period.Human brain mapping · 2022Article
- Advanced Brain Imaging in Preterm Infants: A Narrative Review of Microstructural and Connectomic Disruption.Children (Basel, Switzerland) · 2022Review
- Perinatal stroke: mapping and modulating developmental plasticity.Nature reviews. Neurology · 2021Review
- Cortical Gray Matter Injury in Encephalopathy of Prematurity: Link to Neurodevelopmental Disorders.Frontiers in neurology · 2020Review
- Structural and functional connectivity of motor circuits after perinatal stroke: A machine learning study.NeuroImage. Clinical · 2020Article
- Sleep State Modulates Resting-State Functional Connectivity in Neonates.Frontiers in neuroscience · 2020Article
- Neonatal brain injury and aberrant connectivity.NeuroImage · 2019Review
- Sensory-motor network functional connectivity in children with unilateral cerebral palsy secondary to perinatal stroke.NeuroImage. Clinical · 2019Article
- Methodological challenges in the comparison of infant fMRI across age groups.Developmental cognitive neuroscience · 2018Review
- Recent advances in the use of MRI to assess early human cortical development.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2018Review
- Somatotopic Mapping of the Developing Sensorimotor Cortex in the Preterm Human Brain.Cerebral cortex (New York, N.Y. : 1991) · 2018Article
- Disruption to functional networks in neonates with perinatal brain injury predicts motor skills at 8 months.NeuroImage. Clinical · 2018Article
- A novel sensor design for accurate measurement of facial somatosensation in pre-term infants.PloS one · 2018Article
- Article
- Understanding Brain Reorganization in Infants With Perinatal Stroke Through Neuroexcitability and Neuroimaging.Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association · 2017Article
- Clinical neuroimaging in the preterm infant: Diagnosis and prognosis.NeuroImage. Clinical · 2017Review
- Diffusion tensor imaging-based assessment of white matter tracts and visual-motor outcomes in very preterm neonates.Neuroradiology · 2016Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe objective of the study was to characterize alterations of structural and functional connectivity within the developing sensori-motor system in infants with focal perinatal brain injury and at high risk of cerebral palsy.
methodsFunctional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) data were used to study the developing functional and structural connectivity framework in six infants born prematurely at term equivalent age. This was first characterised in three infants without focal pathology, which was then compared to that derived from three infants with unilateral haemorrhagic parenchymal infarction and a subsequent focal periventricular white matter lesion who developed later haemiparesis.
resultsFunctional responses to passive hand movement were in the contralateral perirolandic cortex, regardless of focal pathology. In infants with unilateral periventricular injury, afferent thalamo-cortical tracts appeared to have developed compensatory trajectories which circumvented areas of damage. In contrast, efferent corticospinal tracts showed marked asymmetry at term equivalent age following focal brain injury. Sensori-motor network analysis suggested that inter-hemispheric functional connectivity is largely preserved despite pathology and that impairment may be associated with adverse neurodevelopmental outcome.
conclusionFollowing focal perinatal brain injury, altered structural and functional connectivity is already present and can be characterized with MRI at term equivalent age. The results of this small case series suggest that these techniques may provide valuable new information about prognosis and the pathophysiology underlying cerebral palsy.
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