ArticleJournal of agricultural and food chemistry2014
Quantitative comparison and metabolite profiling of saponins in different parts of the root of Panax notoginseng.
Article in Journal of agricultural and food chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 109 citations in OpenAlex.
- Metagenomics reveals an interaction among rhizosphere microbial community, soil properties and active ingredients in a medicinal cropJournal of ginseng research · 2026Article
- Sustainable Production of Ginsenosides: Advances in Biosynthesis and Metabolic Engineering.Plants (Basel, Switzerland) · 2025Review
- PnNAC2 promotes the biosynthesis of Panax notoginseng saponins and induces early flowering.Plant cell reports · 2024Article
- PnMYB4 negatively modulates saponin biosynthesis inHorticulture research · 2023Article
- Beneficial effects of Panax notoginseng (Burkill) F. H. Chen flower saponins in rats with metabolic hypertension by inhibiting the activation of the renin-angiotensin-aldosterone system through complement 3.BMC complementary medicine and therapies · 2023Article
- Discrimination and Evaluation of WildInternational journal of analytical chemistry · 2023Article
- A molecular network-based pharmacological study on the protective effect ofFrontiers in pharmacology · 2023Article
- Highly Regioselective Biotransformation of Protopanaxadiol-type and Protopanaxatriol-type Ginsenosides in the Underground Parts ofACS omega · 2022Article
- Quantitative Comparison and Chemical Profile of Different Botanical Parts ofFrontiers in nutrition · 2022Article
- Visualizing the distributions and spatiotemporal changes of metabolites inJournal of ginseng research · 2021Article
- Comprehensive Investigation on Ginsenosides in Different Parts of a Garden-Cultivated Ginseng Root and Rhizome.Molecules (Basel, Switzerland) · 2021Article
- Comparative Research of Chemical Profiling in Different Parts ofMolecules (Basel, Switzerland) · 2021Article
- Fermentation of Panax notoginseng root extract polysaccharides attenuates oxidative stress and promotes type I procollagen synthesis in human dermal fibroblast cells.BMC complementary medicine and therapies · 2021Article
- Phytochemical analysis ofJournal of ginseng research · 2021Review
- Role of Bioactive Constituents ofFrontiers in pharmacology · 2021Review
- Stem-leaves of Panax as a rich and sustainable source of less-polar ginsenosides: comparison of ginsenosides fromJournal of ginseng research · 2021Article
- Protective Effect of Total Panax Notoginseng Saponins on Retinal Ganglion Cells of an Optic Nerve Crush Injury Rat Model.BioMed research international · 2021Article
- Metabolomes and transcriptomes revealed the saponin distribution in root tissues ofJournal of ginseng research · 2020Article
- Unraveling dynamic metabolomes underlying different maturation stages of berries harvested fromJournal of ginseng research · 2020Article
- Chemical and bioactive comparison ofJournal of ginseng research · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Although both rhizome and root of Panax notoginseng are officially utilized as notoginseng in "Chinese Pharmacopoeia", individual parts of the root were differently used in practice. To provide chemical evidence for the differentiated usage, quantitative comparison and metabolite profiling of different portions derived from the whole root, as well as commercial samples, were carried out, showing an overall higher content of saponins in rhizome, followed by main root, branch root, and fibrous root. Ginsenoside Rb2 was proposed as a potential marker with a content of 0.5 mg/g as a threshold value for differentiating rhizome from other parts. Multivariate analysis of the metabolite profile further suggested 32 saponins as potential markers for the discrimination of different parts of notoginseng. Collectively, the study provided comprehensive chemical evidence for the distinct usage of different parts of notoginseng and, hence, is of great importance for the rational application and exploitation of individual parts of notoginseng.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.