Evidence map›Paper›PMID 25118180›Full record

ArticleNature communications2014

Compact genome of the Antarctic midge is likely an adaptation to an extreme environment.

Joanna L Kelley, Justin T Peyton, Anna-Sophie Fiston-Lavier, Nicholas M Teets, Muh-Ching Yee, J Spencer Johnston, Carlos D Bustamante, Richard E Lee, David L Denlinger

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 185 citations in OpenAlex.

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  19. TheInsects · 2024
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Joanna L Kelley1] Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, California 94305, USA [2] School of Biological Sciences, Washington State University, 100 Dairy Road, Pullman, Washington 99164, USA.
Justin T Peyton1] Department of Entomology, Ohio State University, 300 Aronoff Laboratory, 318W. 12th Avenue, Columbus, Ohio 43210, USA [2] Department of Evolution, Ecology and Organismal Biology, Ohio State University, 300 Aronoff Laboratory, 318W. 12th Avenue, Columbus, Ohio 43210, USA [3].
Anna-Sophie Fiston-Lavier1] Department of Biology, Stanford University, 371 Serra St., Stanford, California 94305, USA [2] Institut des Sciences de l'Evolution, UMR5554 CNRS-Université Montpellier 2, Montpellier Cedex 05, France [3].
Nicholas M Teets1] Department of Entomology, Ohio State University, 300 Aronoff Laboratory, 318W. 12th Avenue, Columbus, Ohio 43210, USA [2] Department of Entomology and Nematology, University of Florida, Gainesville, Florida 32611, USA.
Muh-Ching Yee1] Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, California 94305, USA [2] Department of Plant Biology, Carnegie Institution for Science, Stanford, California 94305, USA.
J Spencer JohnstonDepartment of Entomology, Texas A&M University, College Station, Texas 77843, USA.
Carlos D BustamanteDepartment of Genetics, Stanford University, 300 Pasteur Drive, Stanford, California 94305, USA.
Richard E LeeDepartment of Zoology, Miami University, Oxford, Ohio 45056, USA.
David L Denlinger1] Department of Entomology, Ohio State University, 300 Aronoff Laboratory, 318W. 12th Avenue, Columbus, Ohio 43210, USA [2] Department of Evolution, Ecology and Organismal Biology, Ohio State University, 300 Aronoff Laboratory, 318W. 12th Avenue, Columbus, Ohio 43210, USA.
Stanford University · USThe Ohio State University · USMiami University · USTexas A&M University · US

Funding

Dating selection pressures in recent human evolutionF32GM087069 · NIGMS · UNIVERSITY OF CHICAGO · PI KELLEY, JOANNA L · 2010 to 2011
$99k
NIGMS NIH HHS F32 GM087069NIGMS NIH HHS NIH NRSA GM087069
6 · The paper itself

Abstract

The midge, Belgica antarctica, is the only insect endemic to Antarctica, and thus it offers a powerful model for probing responses to extreme temperatures, freeze tolerance, dehydration, osmotic stress, ultraviolet radiation and other forms of environmental stress. Here we present the first genome assembly of an extremophile, the first dipteran in the family Chironomidae, and the first Antarctic eukaryote to be sequenced. At 99 megabases, B. antarctica has the smallest insect genome sequenced thus far. Although it has a similar number of genes as other Diptera, the midge genome has very low repeat density and a reduction in intron length. Environmental extremes appear to constrain genome architecture, not gene content. The few transposable elements present are mainly ancient, inactive retroelements. An abundance of genes associated with development, regulation of metabolism and responses to external stimuli may reflect adaptations for surviving in this harsh environment.

Indexed as

Cold TemperatureEnvironmentAcclimatizationAdaptation, PhysiologicalAnimalsAntarctic RegionsChironomidaeDNAGenes, InsectGenome, InsectIntronsMultigene FamilyDNA

Identifiers

PMID25118180
PMCPMC4164542
OpenAlexW2104602847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.