ReviewAnnals of the New York Academy of Sciences2014
An evolving perspective about the origins of childhood undernutrition and nutritional interventions that includes the gut microbiome.
Review in Annals of the New York Academy of Sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 67 citations in OpenAlex.
- Gut Bacterial Diversity and Growth among Preschool Children in Burkina Faso.The American journal of tropical medicine and hygiene · 2020Trial
- Trial
- Preliminary study on the modulation of diet-induced malnutrition in BALB/c mice using a probiotic consortium: a physiological, biochemical, histopathological, and gut microbiota evaluation.World journal of microbiology & biotechnology · 2026Article
- Resilience and brain health in global populations.Nature medicine · 2025Review
- The Prevalence and Determinants of Undernutrition Among Infants and Children Aged 6 Months to 5 Years in Sub-Saharan African Countries: A Systematic Scoping Review.Nutrition reviews · 2025Article
- Stunting is associated with persistent and transferable alterations in the gut microbiome.Gut pathogens · 2025Article
- Determinants of Child Growth in Palestine (Ages 5-17): A Structural Equation Modeling Approach to Food Insecurity, Nutrition, and Socioeconomic Factors.Children (Basel, Switzerland) · 2025Article
- Microbiome-directed food to promote sustained recovery in children with uncomplicated acute malnutrition: protocol for a randomized controlled trial in Burkina Faso.BMC nutrition · 2025Article
- Review
- Interactions with alloparents are associated with the diversity of infant skin and fecal bacterial communities in Chicago, United States.American journal of human biology : the official journal of the Human Biology Council · 2025Article
- Birth and household exposures are associated with changes to skin bacterial communities during infancy.Evolution, medicine, and public health · 2025Article
- The forgotten link: how the oral microbiome shapes childhood growth and development.Frontiers in oral health · 2025Review
- Relationship of stunting with water, sanitation, and hygiene (WASH) practices among children under the age of five: a cross-sectional study in Southern Punjab, Pakistan.BMC public health · 2023Article
- Intestinal flora and linear growth in children.Frontiers in pediatrics · 2023Review
- Exploratory Analysis of Selected Components of the mTOR Pathway Reveals Potentially Crucial Associations with Childhood Malnutrition.Nutrients · 2022Article
- Malnutrition and Gut Microbiota in Children.Nutrients · 2021Review
- The Role of Immunobiotics and Postbiotics in the Recovery of Immune Cell Populations From Respiratory Mucosa of Malnourished Hosts: Effect on the Resistance Against Respiratory Infections.Frontiers in nutrition · 2021Review
- Plasma Kynurenine to Tryptophan Ratio Is Negatively Associated with Linear Growth of Children Living in a Slum of Bangladesh: Results from a Community-Based Intervention Study.The American journal of tropical medicine and hygiene · 2020Article
- Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 3 countries.
Funding
Abstract
The Sackler Institute for Nutrition Science and the World Health Organization (WHO) have worked together to formulate a research agenda for nutrition science. Undernutrition of children has profound effects on health, development, and achievement of full human capacity. Undernutrition is not simply caused by a lack of food, but results from a complex interplay of intra- and intergenerational factors. Representative preclinical models and comprehensive well-controlled longitudinal clinical studies are needed to further understand the contributions and the interrelationships among these factors and to develop interventions that are effective and durable. This paper summarizes work on mechanisms underlying the varied manifestations of childhood undernutrition and discusses current gaps in knowledge and challenges to our understanding of undernutrition and infection/immunity throughout the human life cycle, focusing on early childhood growth. It proposes a series of basic and clinical studies to address this global health challenge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.