ArticleActa biomaterialia2014
Antibody-functionalized peptidic membranes for neutralization of allogeneic skin antigen-presenting cells.
Article in Acta biomaterialia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 66 citations in OpenAlex.
- Zinc-Mediated Loading and Release of His-Tagged Recombinant Proteins in Self-Assembling Peptide Coacervates.ACS applied bio materials · 2026Article
- Fibril-Guided Three-Dimensional Assembly of Human Fibroblastic Reticular Cells.ACS applied bio materials · 2024Article
- Advancements in self-assembling peptides: Bridging gaps in 3D cell culture and electronic device fabrication.Journal of biomaterials applications · 2024Review
- Nanoparticle-based T cell immunoimaging and immunomodulatory for diagnosing and treating transplant rejection.Heliyon · 2024Review
- Tracking macrophages in diabetic neuropathy with two-color nanoemulsions for near-infrared fluorescent imaging and microscopy.Journal of neuroinflammation · 2021Article
- Electrospun Nanofibers for Cancer Therapy.Advances in experimental medicine and biology · 2021Review
- Self-assemble peptide biomaterials and their biomedical applications.Bioactive materials · 2019Review
- A genetically engineered Fc-binding amphiphilic polypeptide for congregating antibodies in vivo.Acta biomaterialia · 2019Article
- Toward reducing biomaterial antigenic potential: a miniaturized Fc-binding domain for local deposition of antibodies.Biomaterials science · 2019Article
- Synthesis, physicochemical properties and ocular pharmacokinetics of thermosensitive in situ hydrogels for ganciclovir in cytomegalovirus retinitis treatment.Drug delivery · 2018Article
- Introducing copper and collagen (RSC advances · 2018Article
- Stimulation of wound healing using bioinspired hydrogels with basic fibroblast growth factor (bFGF).International journal of nanomedicine · 2018Article
- Article
- Local retention of antibodies in vivo with an injectable film embedded with a fluorogen-activating protein.Journal of controlled release : official journal of the Controlled Release Society · 2016Article
- Expansile crosslinked polymersomes for pH sensitive delivery of doxorubicin.Biomaterials science · 2016Article
- Sundew-Inspired Adhesive Hydrogels Combined with Adipose-Derived Stem Cells for Wound Healing.ACS applied materials & interfaces · 2016Article
- Article
- Advances in drug delivery system for platinum agents based combination therapy.Cancer biology & medicine · 2015Review
- Biocompatible fluorescent supramolecular nanofibrous hydrogel for long-term cell tracking and tumor imaging applications.Scientific reports · 2015Article
- Hydrolysable core crosslinked particle for receptor-mediated pH-sensitive anticancer drug delivery.New journal of chemistry = Nouveau journal de chimie · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
We report herein application of an in situ material strategy to attenuate allograft T cell responses in a skin transplant mouse model. Functionalized peptidic membranes were used to impede trafficking of donor antigen-presenting cells (dAPCs) from skin allografts in recipient mice. Membranes formed by self-assembling peptides (SAPs) presenting antibodies were found to remain underneath grafted skins for up to 6 days. At the host-graft interface, dAPCs were targeted by using a monoclonal antibody that binds to a class II major histocompatibility complex (MHC) molecule (I-A(d)) expressed exclusively by donor cells. Using a novel cell labeling near-infrared nanoemulsion, we found more dAPCs remained in allografts treated with membranes loaded with anti-I-A(d) antibodies than without. In vitro, dAPCs released from skin explants were found adsorbed preferentially on anti-I-A(d) antibody-loaded membranes. Recipient T cells from these mice produced lower concentrations of interferon-gamma cultured ex vivo with donor cells. Taken together, the data indicate that the strategy has the potential to alter the natural course of rejection immune mechanisms in allogeneic transplant models.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.