Evidence map›Paper›PMID 25117679›Full record

ArticleDevelopmental cell2014

A role for β3-integrins in linking breast development and cancer.

Ahmet Ucar, Charles H Streuli

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Ahmet UcarWellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Charles H StreuliWellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK. Electronic address: cstreuli@manchester.ac.uk.

Funding

Breast Cancer Now 2013MAYPR029
6 · The paper itself

Abstract

Pregnancy induces a rapid and controlled expansion of mammary stem cells. In this issue of Developmental Cell, Desgrosellier et al. (2014) show that β3-integrin is required downstream of hormonal signaling and TGFβ2 to regulate mammary stem cell number and alveolar development specifically during early pregnancy.

Indexed as

AnimalsCell Transformation, NeoplasticFemaleHumansIntegrin alphaVbeta3Mammary Glands, AnimalPregnancySnail Family Transcription FactorsStem CellsTranscription FactorsIntegrin alphaVbeta3Snail Family Transcription FactorsTranscription Factors

Identifiers

PMID25117679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.