Evidence map›Paper›PMID 25117645›Full record

ReviewJournal of assisted reproduction and genetics2014

A multi-faceted approach to understanding male infertility: gene mutations, molecular defects and assisted reproductive techniques (ART).

Eisa Tahmasbpour, Dheepa Balasubramanian, Ashok Agarwal

Abstract readReview
In one paragraph

Review in Journal of assisted reproduction and genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Drivers of systemic male-female allele frequency divergence in humans.bioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Decellularized testicular bio-scaffolds driveFrontiers in bioengineering and biotechnology · 2026
    Article
  10. Article
  11. Review
  12. The Study ofInternational journal of fertility & sterility · 2025
    Article
  13. Article
  14. Ameliorative effects of vitamin C and garlic (Frontiers in veterinary science · 2025
    Article
  15. Article
  16. Article
  17. Human Papillomavirus and Male Infertility: What Do We Know?International journal of molecular sciences · 2023
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eisa TahmasbpourDepartment of Biology, Islamic Azad University, Sari, Iran.
Dheepa Balasubramanian
Ashok Agarwal

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe assisted reproductive techniques aimed to assist infertile couples have their own offspring carry significant risks of passing on molecular defects to next generations.

resultsNovel breakthroughs in gene and protein interactions have been achieved in the field of male infertility using genome-wide proteomics and transcriptomics technologies.

conclusionMale Infertility is a complex and multifactorial disorder. SIGNIFICANCE: This review provides a comprehensive, up-to-date evaluation of the multifactorial factors involved in male infertility. These factors need to be first assessed and understood before we can successfully treat male infertility.

Indexed as

MutationReproductive Techniques, AssistedAneuploidyDNA, MitochondrialEpigenomicsHumansInfertility, MaleMaleMicroRNAsRNA, Small InterferingSex Chromosome AberrationsSpermatozoaDNA, MitochondrialMicroRNAsRNA, Small Interfering

Identifiers

PMID25117645
PMCPMC4156950

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.