ReviewBioconjugate chemistry2014
Surface engineering of graphene-based nanomaterials for biomedical applications.
Review in Bioconjugate chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Recent Advances in Integrating Graphene into Polymeric Nanocomposite Hydrogels for Biomedical Applications.Macromolecular bioscience · 2026Review
- Green PEGylation of Graphene Oxide via Diels-Alder Chemistry in Deep Eutectic Solvents for pH-Responsive Doxorubicin Delivery.TheScientificWorldJournal · 2026Article
- Graphene Oxide (GO) Layered Bioconjugates: An Effective Strategy for Delivering p53 Gene for Adenocarcinoma.Recent patents on nanotechnology · 2025Article
- Advances in nanomaterial-mediated CRISPR/Cas delivery: from lipid nanoparticles to vesicle-derived systems.Frontiers in bioengineering and biotechnology · 2025Review
- Advances in Nanotheranostic Systems for Concurrent Cancer Imaging and Therapy: An Overview of the Last 5 Years.Molecules (Basel, Switzerland) · 2024Review
- Retinal Prostheses: Engineering and Clinical Perspectives for Vision Restoration.Sensors (Basel, Switzerland) · 2023Review
- On using non-Kekulé triangular graphene quantum dots for scavenging hazardous sulfur hexafluoride components.Heliyon · 2023Article
- Functionalized Carbon Nanoparticles as Theranostic Agents and Their Future Clinical Utility in Oncology.Bioengineering (Basel, Switzerland) · 2023Review
- A convergent synthetic platform for dual anticancer drugs functionalized by reduced graphene nanocomposite delivery for hepatocellular cancer.Drug delivery · 2021Article
- Phototherapy Combined with Carbon Nanomaterials (1D and 2D) and their Applications in Cancer Therapy.Materials (Basel, Switzerland) · 2020Review
- Inducing endoplasmic reticulum stress in cancer cells using graphene oxide-based nanoparticles.Nanoscale advances · 2020Article
- The Impact of Engineered Silver Nanomaterials on the Immune System.Nanomaterials (Basel, Switzerland) · 2020Review
- Surface-Induced in Situ Sonothermodynamically Controlled Functionalized Graphene Oxide for in Vitro Cytotoxicity and Antioxidant Evaluations.ACS omega · 2019Article
- 2D Materials in Development of Electrochemical Point-of-Care Cancer Screening Devices.Micromachines · 2019Review
- Graphene oxide nanohybrids for electron transfer-mediated antimicrobial activity.Nanoscale advances · 2019Article
- Dual Drugs Anticancer Nanoformulation using Graphene Oxide-PEG as Nanocarrier for Protocatechuic Acid and Chlorogenic Acid.Pharmaceutical research · 2019Article
- Optically Active Nanomaterials for Bioimaging and Targeted Therapy.Frontiers in bioengineering and biotechnology · 2019Review
- A Review on Graphene-Based Nanomaterials in Biomedical Applications and Risks in Environment and Health.Nano-micro letters · 2018Article
- Magnetic chitosan/graphene oxide composite loaded with novel photosensitizer for enhanced photodynamic therapy.RSC advances · 2018Article
- Positron emission tomography and nanotechnology: A dynamic duo for cancer theranostics.Advanced drug delivery reviews · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Graphene-based nanomaterials have attracted tremendous interest over the past decade due to their unique electronic, optical, mechanical, and chemical properties. However, the biomedical applications of these intriguing nanomaterials are still limited due to their suboptimal solubility/biocompatibility, potential toxicity, and difficulties in achieving active tumor targeting, just to name a few. In this Topical Review, we will discuss in detail the important role of surface engineering (i.e., bioconjugation) in improving the in vitro/in vivo stability and enriching the functionality of graphene-based nanomaterials, which can enable single/multimodality imaging (e.g., optical imaging, positron emission tomography, magnetic resonance imaging) and therapy (e.g., photothermal therapy, photodynamic therapy, and drug/gene delivery) of cancer. Current challenges and future research directions are also discussed and we believe that graphene-based nanomaterials are attractive nanoplatforms for a broad array of future biomedical applications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.