Trial reportPsychotherapy and psychosomatics2014
Tai chi meditation effects on nuclear factor-κB signaling in lonely older adults: a randomized controlled trial.
Registry-linked trialAbstract readLetterRandomized Controlled Trial
In one paragraph
Trial report in Psychotherapy and psychosomatics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01204021 (Managing Stress and Social Ties for Health Aging), which is not on this map. Cited by 25 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Managing Stress and Social Ties for Health Aging
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Effectiveness of Mind-Body Exercise on Health-Related Quality of Life and Mental Health During and After Breast Cancer Treatment: An Umbrella Review of Meta-Analyses for Randomized Controlled Trials.Worldviews on evidence-based nursing · 2025Pooled it
- Systematic Review of Efficacy of Interventions for Social Isolation of Older Adults.Frontiers in psychology · 2021Pooled it
- The Effect of Tai Chi Chuan on Negative Emotions in Non-Clinical Populations: A Meta-Analysis and Systematic Review.International journal of environmental research and public health · 2019Pooled it
- A Randomized Trial of Tai Chi on Preventing Hypertension and Hyperlipidemia in Middle-Aged and Elderly Patients.International journal of environmental research and public health · 2021Trial
- Tai Chi Chih Compared With Cognitive Behavioral Therapy for the Treatment of Insomnia in Survivors of Breast Cancer: A Randomized, Partially Blinded, Noninferiority Trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017Trial
- Mindfulness meditation and improvement in sleep quality and daytime impairment among older adults with sleep disturbances: a randomized clinical trial.JAMA internal medicine · 2015Trial
- Mindfulness-based intervention for prodromal sleep disturbances in older adults: design and methodology of a randomized controlled trial.Contemporary clinical trials · 2014Trial
- Loneliness and all-cause mortality in the United States.PloS one · 2026Article
- The Science of Tai Chi and Qigong as Whole Person Health-Part II: Evidence Gaps and Opportunities for Future Research and Implementation.Journal of integrative and complementary medicine · 2025Review
- The Science of Tai Chi andJournal of integrative and complementary medicine · 2025Review
- Unmet Needs in Spondyloarthritis: Pathogenesis, Clinical Trial Design, and Nonpharmacologic Therapy.The Journal of rheumatology · 2024Review
- From inflammatory signaling to neuronal damage: Exploring NLR inflammasomes in ageing neurological disorders.Heliyon · 2024Review
- Heat of the night: sleep disturbance activates inflammatory mechanisms and induces pain in rheumatoid arthritis.Nature reviews. Rheumatology · 2023Review
- Beneficial Effects and Potential Mechanisms of Tai Chi on Lower Limb Osteoarthritis: A Biopsychosocial Perspective.Chinese journal of integrative medicine · 2023Review
- Sleep disruption induces activation of inflammation and heightens risk for infectious disease: Role of impairments in thermoregulation and elevated ambient temperature.Temperature (Austin, Tex.) · 2023Article
- The effects of meditation on individuals facing loneliness: a scoping review.BMC psychology · 2021Article
- An observational study protocol to explore loneliness and systemic inflammation in an older adult population with chronic venous leg ulcers.BMC geriatrics · 2021Article
- Regular Tai Chi Practice Is Associated With Improved Memory as Well as Structural and Functional Alterations of the Hippocampus in the Elderly.Frontiers in aging neuroscience · 2020Article
- Biobehavioral effects of Tai Chi Qigong in men with prostate cancer: Study design of a three-arm randomized clinical trial.Contemporary clinical trials communications · 2019Article
- Tai Chi Improves Brain Metabolism and Muscle Energetics in Older Adults.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
David S BlackDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, Calif., USA.
Michael R Irwin
Richard Olmstead
Ellen Ji
Elizabeth Crabb Breen
Sarosh J Motivala
Funding
UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0MUCLA OLDER AMERICANS INDEPENDENCE CENTERP30AG028748 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI REUBEN, DAVID B. · 2006 to 2017
$9.8MAging: Sleep and Inflammatory Mechanisms in Depression PreventionR01AG026364 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2005 to 2015
$5.8MSleep, Inflamation, and Depression Occurrence in Breast Cancer SurvivorsR01CA160245 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2012 to 2016
$3.9MChronic Moderate Sleep Restriction in Older Long and Older Average SleepersR01HL095799 · NHLBI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI IRWIN, MICHAEL R, JEAN-LOUIS, GIRARDIN · 2011 to 2015
$3.8MMechanisms of Sleep Disruption HyperalgesiaR01DA032922 · NIDA · JOHNS HOPKINS UNIVERSITY · PI IRWIN, MICHAEL R, SMITH, MICHAEL T · 2012 to 2016
$2.7MTai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune MechanismsR01CA119159 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2006 to 2010
$2.2MSubjective Social Isolation and Sleep Disturbances: Inflammatory Mechanisms in AgR01AG034588 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2009 to 2013
$1.9MPost-Graduate Training Program in Psychoneuroimmunology and Mental HealthT32MH019925 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 1997 to 2012
$1.7MAging: Insomnia Treatment and Energy BalanceK23AG027860 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MOTIVALA, SAROSH J · 2006 to 2010
$609kNCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1TR000124NCI NIH HHS R01 CA119159NCI NIH HHS R01-CA119159NCI NIH HHS R01 CA160245NCI NIH HHS R01-CA160245-01NHLBI NIH HHS R01 HL095799NHLBI NIH HHS R01-HL095799NIA NIH HHS K23 AG027860NIA NIH HHS P30 AG028748NIA NIH HHS P30-AG028748NIA NIH HHS R01 AG026364NIA NIH HHS R01-AG026364NIA NIH HHS R01 AG034588NIA NIH HHS R01-AG034588NIDA NIH HHS R01 DA032922NIDA NIH HHS R01-DA032922-01NIMH NIH HHS T32 MH019925NIMH NIH HHS T32-MH19925
Abstract
PubMed holds no abstract for this paper.
Indexed as
LonelinessTai JiAgedFemaleHumansMaleNF-kappa BStress, PsychologicalNF-kappa B
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
NCT01204021ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.