ArticleScientific reports2014
Genome-wide genotype and sequence-based reconstruction of the 140,000 year history of modern human ancestry.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 63 citations in OpenAlex.
- Admixture mapping identifies African and Amerindigenous local ancestry loci associated with fetal growth.Human genetics · 2021Trial
- Unlocking Ethiopia's genomic landscape and its global significance: a call for inclusive genomics research.Human genomics · 2026Review
- Maternal obesity and ancestry distance in influencing birth outcomes.International journal of obesity (2005) · 2025Observational
- Dynamic clustering of genomics cohorts beyond race, ethnicity-and ancestry.BMC medical genomics · 2025Article
- The Frequency ofPharmaceutics · 2024Article
- Personalized medicine and nutrition in hepatology for preventing chronic liver disease in Mexico.Frontiers in nutrition · 2024Review
- Including diverse and admixed populations in genetic epidemiology research.Genetic epidemiology · 2022Article
- Ethnic Diversity and Warfarin Pharmacogenomics.Frontiers in pharmacology · 2022Review
- Genetic landscape of Gullah African Americans.American journal of physical anthropology · 2021Article
- Maternal cardiometabolic factors and genetic ancestry influence epigenetic aging of the placenta.Journal of developmental origins of health and disease · 2021Observational
- GADMA: Genetic algorithm for inferring demographic history of multiple populations from allele frequency spectrum data.GigaScience · 2020Article
- Counting Oceanians of Non-European, Non-Asian Descent (ONENA) in the South Pacific to Make Them Count in Global Health.Tropical medicine and infectious disease · 2019Article
- Genetic history of Chad.American journal of physical anthropology · 2018Article
- African genetic diversity provides novel insights into evolutionary history and local adaptations.Human molecular genetics · 2018Review
- Genetic Ancestry of Hadza and Sandawe Peoples Reveals Ancient Population Structure in Africa.Genome biology and evolution · 2018Article
- Re-analysis of Whole Genome Sequence Data From 279 Ancient Eurasians Reveals Substantial Ancestral Heterogeneity.Frontiers in genetics · 2018Article
- Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans.Nature communications · 2017Article
- Advancing stroke genomic research in the age of Trans-Omics big data science: Emerging priorities and opportunities.Journal of the neurological sciences · 2017Review
- Diversity and inclusion in genomic research: why the uneven progress?Journal of community genetics · 2017Article
- The genomic landscape of African populations in health and disease.Human molecular genetics · 2017Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
We investigated ancestry of 3,528 modern humans from 163 samples. We identified 19 ancestral components, with 94.4% of individuals showing mixed ancestry. After using whole genome sequences to correct for ascertainment biases in genome-wide genotype data, we dated the oldest divergence event to 140,000 years ago. We detected an Out-of-Africa migration 100,000-87,000 years ago, leading to peoples of the Americas, east and north Asia, and Oceania, followed by another migration 61,000-44,000 years ago, leading to peoples of the Caucasus, Europe, the Middle East, and south Asia. We dated eight divergence events to 33,000-20,000 years ago, coincident with the Last Glacial Maximum. We refined understanding of the ancestry of several ethno-linguistic groups, including African Americans, Ethiopians, the Kalash, Latin Americans, Mozabites, Pygmies, and Uygurs, as well as the CEU sample. Ubiquity of mixed ancestry emphasizes the importance of accounting for ancestry in history, forensics, and health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.