Evidence map›Paper›PMID 25116086›Full record

ArticleMedicine and science in sports and exercise2015

Physical activity and chronic prostatitis/chronic pelvic pain syndrome.

Ran Zhang, Andrea K Chomistek, Jordan D Dimitrakoff, Edward L Giovannucci, Walter C Willett, Bernard A Rosner, Kana Wu

Open access · greenAbstract read
In one paragraph

Article in Medicine and science in sports and exercise, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
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  13. Review
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  16. Review
  17. Management of Chronic Prostatitis (CP).Current urology reports · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Ran Zhang1Department of Nutrition, Harvard School of Public Health, Boston, MA; 2Department of Epidemiology, Harvard School of Public Health, Boston, MA; 3Department of Epidemiology and Biostatistics, School of Public Health, Indiana University, Bloomington, IN; 4Department of Obstetrics, Gynecology, and Reproductive Biology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA; 5Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA; 6Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA; and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA.
Andrea K Chomistek
Jordan D Dimitrakoff
Edward L Giovannucci
Walter C Willett
Bernard A Rosner
Kana Wu
Brigham and Women's Hospital · USHarvard University · USBeth Israel Deaconess Medical Center · USIndiana University Bloomington · US

Funding

Validity of Diet and Activity Measures in WomenP01CA055075 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI WILLETT, WALTER C. · 1991 to 2009
$41.8M
Cancer Epidemiology Cohort in Male Health ProfessionalsUM1CA167552 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI WILLETT, WALTER C. · 2012 to 2016
$11.5M
Energy Balance-Related Hormones & Prostate Cancer Incidence & ProgressionR01CA133891 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI GIOVANNUCCI, EDWARD · 2008 to 2012
$3.3M
NCI NIH HHS P01 CA055075NCI NIH HHS R01 CA133891NCI NIH HHS UM1 CA167552
6 · The paper itself

Abstract

purposeChronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent urologic disorder among men, but its etiology is still poorly understood. Our objective was to examine the relation between physical activity and incidence of CP/CPPS in a large cohort of male health professionals.

methodsWe conducted a prospective cohort study among men in the Health Professionals Follow-up Study followed from 1986 to 2008. The study population included 20,918 men who completed all CP/CPPS questions on the 2008 questionnaire. Leisure-time physical activity, including type and intensity of activity, was measured by questionnaire in 1986. A National Institute of Health Chronic Prostatitis Symptom Index pain score was calculated on the basis of the responses on the 2008 questionnaire. Participants with pain scores ≥8 were considered CP/CPPS cases (n = 689).

resultsHigher leisure-time physical activity was associated with lower risk of CP/CPPS. The multivariable-adjusted odds ratio comparing >35.0 to ≤3.5 MET·h·wk of physical activity was 0.72 (95% confidence interval, 0.56-0.92; P for trend <0.001). Observed inverse associations between physical activity and CP/CPPS were similar for both moderate- and vigorous-intensity activities. Sedentary behavior, measured as time spent watching television, was not associated with risk of CP/CPPS (P for trend = 0.64).

conclusionsFindings from this study, the first large scale and most comprehensive study to date on this association, suggest that higher levels of leisure-time physical activity may lower risk of CP/CPPS in middle-age and older men.

Indexed as

Motor ActivityAdultAgedChronic DiseaseExerciseFollow-Up StudiesHumansIncidenceLeisure ActivitiesMaleMiddle AgedPelvic PainProspective StudiesProstatitisRisk FactorsSyndrome

Identifiers

PMID25116086
PMCPMC4324388
OpenAlexW1985110430

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.