ReviewJournal of thrombosis and thrombolysis2015
Thromboembolic complications in inflammatory bowel disease.
Review in Journal of thrombosis and thrombolysis, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Epidemiology and Risk Factors of Portal Venous System Thrombosis in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Unraveling the Clinical Puzzle of Cerebral Venous Sinus Thrombosis in Ulcerative Colitis: Insights from a Systematic Review.Asian journal of neurosurgery · 2026Review
- Serum Levels of Coagulation Factors in Patients with Inflammatory Bowel Disease.Iranian journal of pathology · 2026Article
- Compartment Syndrome Secondary to Phlegmasia Cerulea Dolens in a Patient With Crohn's Disease.The American journal of case reports · 2025Article
- Ocular Manifestations of IBD: Pathophysiology, Epidemiology, and Iatrogenic Associations of Emerging Treatment Strategies.Biomedicines · 2024Review
- Cardiovascular manifestations of inflammatory bowel diseases and the underlying pathogenic mechanisms.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Review
- Extensive Unprovoked Thromboembolism in Steroid-Dependent Ulcerative Colitis: A Case Report.Cureus · 2023Article
- Cerebral venous thrombosis secondary to ulcerative colitis: A case report with a literature review.Radiology case reports · 2023Article
- Inflammatory bowel disease and thromboembolic events: a c'lot to learn.Therapeutic advances in gastroenterology · 2022Article
- A nationwide survey concerning the mortality and risk of progressing severity due to arterial and venous thromboembolism in inflammatory bowel disease in Japan.Journal of gastroenterology · 2021Article
- Microbiota Gut-Brain Axis in Ischemic Stroke: A Narrative Review with a Focus about the Relationship with Inflammatory Bowel Disease.Life (Basel, Switzerland) · 2021Review
- Genetic Variants of RPL5 and RPL9 Genes among Saudi Patients Diagnosed with Thrombosis.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2021Article
- Importance of Not MSing Cerebral White Matter Disease in Patients with Inflammatory Bowel Disease.Digestive diseases and sciences · 2020Article
- Cerebral venous sinus thrombosis in a young patient with ulcerative colitis: A case report.Medicine · 2019Article
- Cardiovascular Manifestations of Inflammatory Bowel Disease: Pathogenesis, Diagnosis, and Preventive Strategies.Gastroenterology research and practice · 2019Review
- Bidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke.Journal of neuroinflammation · 2018Review
- Risk of thrombosis and mortality in inflammatory bowel disease.Clinical and translational gastroenterology · 2018Article
- Thromboembolism in active ulcerative colitis.BMJ case reports · 2017Article
- Hormonal Contraception Use is Common Among Patients with Inflammatory Bowel Diseases and an Elevated Risk of Deep Vein Thrombosis.Inflammatory bowel diseases · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with inflammatory bowel disease (IBD) have a 1.5-3.5-fold higher risk of thromboembolism when compared to the non-IBD population and the risk is much more prominent at the time of a flare. Arterial thromboembolism (ischemic stroke, focal white matter ischemia, cardiac ischemia, peripheral vascular disease and mesenteric ischemia) and venous thromboembolism (deep vein thrombosis and pulmonary embolism, cerebral venous sinus thrombosis, retinal, hepatic, portal and mesenteric vein thromboses) belong to the group of underestimated extraintestinal complications in IBD patients, which are associated with a high morbidity and mortality rate (the overall mortality is as high as 25 % per episode). Thromboembolism occurs in younger patients compared to the non-IBD population and has a high recurrence rate. Multiple risk factors are involved in the etiopathogenesis, but the acquired ones play the key role. Congenital alterations do not occur more frequently in IBD patients when compared to the non-IBD population. Standardized guidelines for the prophylaxis of thromboembolism in IBD patients are urgently needed and these should be respected in clinical practice to avoid preventable morbidity and mortality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.