Evidence map›Paper›PMID 25115797›Full record

ArticlePublic health nutrition2015

Anthropometry and body composition of vertically HIV-infected children and adolescents under therapy with and without protease inhibitors.

Lígia Cardoso Dos Reis, Patrícia Helen de Carvalho Rondó, Heloisa Helena de Sousa Marques, Neuber José Segri

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Public health nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Health-Related Physical Fitness Evaluation in HIV-Diagnosed Children and Adolescents: A Scoping Review.International journal of environmental research and public health · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lígia Cardoso Dos Reis1Department of Nutrition,School of Public Health,University of São Paulo,Avenida Dr Arnaldo 715,São Paulo,SP,CEP 01246-904,Brazil.
Patrícia Helen de Carvalho Rondó1Department of Nutrition,School of Public Health,University of São Paulo,Avenida Dr Arnaldo 715,São Paulo,SP,CEP 01246-904,Brazil.
Heloisa Helena de Sousa Marques2Institute of Child Health,School of Medicine,University of São Paulo,São Paulo,SP,Brazil.
Neuber José Segri3Department of Statistics,Federal University of Mato Grosso,Cuiabá,MT,Brazil.
Universidade de São Paulo · BRUniversidade Federal de Mato Grosso · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAlthough the benefits of highly active antiretroviral therapy (HAART) have been documented, it is thought to be associated to disturbances in nutritional status. These disturbances may occur early in life and are poorly understood. The present study aimed to investigate the relationship between anthropometric parameters and body composition of perinatally HIV-infected children and adolescents under HAART, according to use and non-use of protease inhibitors.

designCross-sectional study undertaken between August and December 2007. Demographic, socio-economic, clinical and anthropometric data were collected from the patients. The χ 2 test, Wilcoxon rank sum test (Mann-Whitney) and t test were used to compare the following variables between users and non-users of protease inhibitors: age, gender, per capita income, HAART exposure, antiretroviral therapy adopted in the last three years, CD4 count, viral load, pubertal stage, nutritional status (BMI-for-age, height-for-age, waist and neck circumferences, triceps skinfold thickness, body fat percentage, upper-arm fat area and upper-arm muscle area).

settingAn HIV/AIDS out-patient clinic, São Paulo, Brazil. SUBJECTS: One hundred and fifteen patients (children and adolescents aged 6-19 years).

resultsProtease inhibitors users had a higher prevalence of stunting (P=0.03), lower BMI (P=0.03) and lower percentage of body fat (P=0.05) compared with non-users. There was no statistically significant difference between the HAART regimens and measurements of fat adiposity.

conclusionsThe findings of the study suggest that children and adolescents under protease inhibitors are at higher risk of growth and development deviations, but not at risk of body fat redistribution.

Indexed as

Infectious Disease Transmission, VerticalAdiposityAdolescentAdultAntiretroviral Therapy, Highly ActiveBody Mass IndexBrazilChildCross-Sectional StudiesFemaleGrowth DisordersHIV InfectionsHIV Protease InhibitorsHospitals, PediatricHumansMaleHIV Protease InhibitorsHighly active antiretroviral therapy

Identifiers

PMID25115797
PMCPMC10271505
OpenAlexW2100897198

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.