Evidence map›Paper›PMID 25115766›Full record

ReviewCurrent opinion in anaesthesiology2014

Postoperative ICU management of patients after subarachnoid hemorrhage.

Shaun E Gruenbaum, Fedrico Bilotta

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Current opinion in anaesthesiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05095857 (S-ketamine for Cortical Spreading Depolarisation in Patients With Severe Acute Brain Injury), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05095857 phase4recruitingnot on this mapstarted 2023, after this paper: background citation

S-ketamine for Cortical Spreading Depolarisation in Patients With Severe Acute Brain Injury

TypeinterventionalSponsorRigshospitalet, DenmarkRan2023 to 2028Enrolled400ConditionsSubarachnoid Hemorrhage, Aneurysmal, Intracerebral Hemorrhage, Traumatic Brain InjuryArmsS-ketamine, Isotonic saline (placebo)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Shaun E GruenbaumaDepartment of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut, USA bDepartment of Anesthesiology, Critical Care and Pain Medicine, 'Sapienza' University of Rome, Rome, Italy.
Fedrico Bilotta
Sapienza University of Rome · ITYale University · US

Funding

Research Training in AnesthesiaT32GM086287 · NIGMS · YALE UNIVERSITY · PI ROBERT SCHONBERGER · 2009 to 2026
$3.7M
NIGMS NIH HHS T32 GM086287
6 · The paper itself

Abstract

purpose of reviewThis article reviews recent advances in the postoperative ICU management of patients after subarachnoid hemorrhage (SAH), especially with regards to hemodynamic management, methods of improving neurological outcomes, and management of cardiac and pulmonary complications. RECENT

findingsSeveral hemodynamic monitors and parameters may be useful for guiding volume therapy, including cardiac output, stroke volume variation monitoring, and global end-diastolic volume index. Early goal-directed hemodynamic therapy after SAH has recently been shown to improve clinical outcomes in patients with a poor clinical grade or coexisting cardiopulmonary complications. Recent laboratory and imaging modalities are being developed to identify patients at risk for developing vasospasm after SAH. Evidence for the use of various prophylactic adjuvant therapies to prevent vasospasm, including magnesium, phosphodiesterase 3 inhibitors, and therapeutic hypothermia, is emerging. Intrathecal administration of vasodilators or fibrinolytics may have offered advantages over systemic drug administration in the treatment of vasospasm. Pulmonary and cardiac complications are common after SAH, and are associated with an increased risk of mortality. SUMMARY: The postoperative ICU period after SAH is associated with a significant morbidity and mortality risk, and recent studies have greatly contributed to our understanding of how to optimally manage these patients.

Indexed as

Intensive Care UnitsCritical CareHemodynamicsHumansMonitoring, PhysiologicPostoperative CarePostoperative ComplicationsSubarachnoid Hemorrhage

Identifiers

PMID25115766
PMCPMC4382080
OpenAlexW2019112029

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.