Evidence map›Paper›PMID 25115505›Full record

ArticleEuropean journal of applied physiology2014

G tolerance and the vasoconstrictor reserve.

Patrik Sundblad, Roger Kölegård, Ola Eiken

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of applied physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. The arterial baroreflex and inherent G tolerance.European journal of applied physiology · 2016
    Trial
  2. Review
  3. Review
  4. Observational
  5. Article
  6. Observational
  7. A Cardiac Force Index Applied to the G Tolerance Test and Surveillance among Male Military Aircrew.International journal of environmental research and public health · 2021
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patrik SundbladDepartment of Environmental Physiology, Swedish Aerospace Physiology Centre, School of Technology and Health, Royal Institute of Technology (KTH), Berzelius väg 13, 171 65, Stockholm, Sweden, patsu@kth.se.
Roger Kölegård
Ola Eiken

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBecause leg arterial stiffness is higher in subjects with high G tolerance, we hypothesized that subjects with high G tolerance would have larger capacity for vasoconstriction.

methodsSixteen subjects, eight with high and eight with low G tolerance (H and L group, respectively), were exposed to a cold pressor test (CPT) in supine and upright posture. Heart rate (HR), mean arterial pressure (MAP) and cardiac output (CO) were measured, and total peripheral resistance (TPR) and stroke volume (SV) were calculated.

resultsIn the supine position, CPT increased TPR more in the H group; 31 ± 18% than in the L group; 11 ± 7% (p < 0.05). The L group had larger increases in CO than the H group; 17 ± 16 vs. 3.4 ± 7% (p = 0.06). In the upright position, the H group had a larger MAP response to CPT than the L group; 26 ± 14 vs. 14 ± 7% (p = 0.06). The H group, but not the L group, had significant increases in TPR whereas the L group had significant increases in CO and SV.

conclusionsIn response to CPT, the high G tolerance group elevated MAP by increasing TPR, whereas the low G tolerance group showed a dependency on increased CO. The H group seemed to have a larger vasoconstrictor reserve. The results further suggest that vasoconstrictor reserve capacity could constitute the link between the recent finding that indicates a relationship between G tolerance and arterial distensibility in the legs.

Indexed as

GravitationAdultBlood PressureCardiac OutputCold TemperatureElectromyographyHeart RateHemodynamicsHumansMalePostureVascular ResistanceVasoconstrictionYoung Adult

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.