Evidence map›Paper›PMID 25114844›Full record

ReviewWorld journal of clinical oncology2014

Weight gain following breast cancer diagnosis: Implication and proposed mechanisms.

Grace Makari-Judson, Barry Braun, D Joseph Jerry, Wilson C Mertens

Registry-linked trialOpen access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of clinical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06090747 (Efecto de Una intervención Multidisciplinaria de Estilo de Vida Sobre el Exposoma de Pacientes premenopáusicas Con cáncer de Mama Estadios I-III.), which is not on this map. Cited by 86 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 6 pooled it
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06090747 narecruitingnot on this mapstarted 2023, after this paper: background citation

Efecto de Una intervención Multidisciplinaria de Estilo de Vida Sobre el Exposoma de Pacientes premenopáusicas Con cáncer de Mama Estadios I-III.

TypeinterventionalSponsorInstituto Nacional de Cancerologia de MexicoRan2023 to 2028Enrolled146ConditionsBreast NeoplasmArmsHybrid lifestyle educational multidisciplinary intervention., Hybrid lifestyle personalized multidisciplinary intervention.
3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 6 syntheses or guidelines pooled it, 158 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Benefits of weight loss programs for breast cancer survivors: a systematic reviews and meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
  5. Body weight management in overweight and obese breast cancer survivors.The Cochrane database of systematic reviews · 2020
    Pooled it
  6. Pooled it
  7. Association of patient factors and health-related quality of life with weight changes during chemotherapy for colorectal cancer: secondary analysis of the SCOT trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Article
  16. Article
  17. Review
  18. Article
  19. Determinants of breast and gynecologic cancer survivors' intention to adopt a healthy post-treatment lifestyle.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2026
    Article
  20. Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2026
    Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Grace Makari-JudsonGrace Makari-Judson, Barry Braun, D Joseph Jerry, Wilson C Mertens, The Rays of Hope Center for Breast Cancer Research, Springfield, MA 01107, United States.
Barry BraunGrace Makari-Judson, Barry Braun, D Joseph Jerry, Wilson C Mertens, The Rays of Hope Center for Breast Cancer Research, Springfield, MA 01107, United States.
D Joseph JerryGrace Makari-Judson, Barry Braun, D Joseph Jerry, Wilson C Mertens, The Rays of Hope Center for Breast Cancer Research, Springfield, MA 01107, United States.
Wilson C MertensGrace Makari-Judson, Barry Braun, D Joseph Jerry, Wilson C Mertens, The Rays of Hope Center for Breast Cancer Research, Springfield, MA 01107, United States.
Stimson Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Weight gain occurs in the majority of women following breast cancer treatment. An overview of studies describing weight gain amongst women treated with early to modern chemotherapy regimens is included. Populations at higher risk include women who are younger, closer to ideal body weight and who have been treated with chemotherapy. Weight gain ranges between 1 to 5 kg, and may be associated with change in body composition with gain in fat mass and loss in lean body mass. Women are unlikely to return to pre-diagnosis weight. Possible mechanisms including inactivity and metabolic changes are explored. Potential interventions are reviewed including exercise, dietary changes and pharmacologic agents. Although breast cancer prognosis does not appear to be significantly impacted, weight gain has negative consequences on quality of life and overall health. Future studies should explore change in body composition, metabolism and insulin resistance. Avoiding weight gain in breast cancer survivors following initial diagnosis and treatment should be encouraged.

Indexed as

Breast cancerExerciseInsulin resistanceSurvivorshipWeight gain

Identifiers

PMID25114844
PMCPMC4127600
OpenAlexW2065899189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.