Evidence map›Paper›PMID 25114620›Full record

ReviewPlastic surgery (Oakville, Ont.)2014

Meta-analysis of antibiotic prophylaxis in breast reduction surgery.

Rodger Shortt, Michael J Cooper, Forough Farrokhyar, James Bain

Open access · greenAbstract readReview
PubMed Full text at PMC
In one paragraph

Review in Plastic surgery (Oakville, Ont.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. The "Mosque Tower Pattern" for the Preoperative Marking of Reduction Mammaplasty.Plastic and reconstructive surgery. Global open · 2024
    Article
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  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rodger ShorttDivision of Plastic Surgery, McMaster University, Hamilton, Ontario.
Michael J CooperDivision of Plastic Surgery, McMaster University, Hamilton, Ontario.
Forough FarrokhyarDepartment of Surgery, McMaster University, Hamilton, Ontario ; Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario.
James BainDivision of Plastic Surgery, McMaster University, Hamilton, Ontario.
McMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast reduction surgery is a very common procedure; however, there is still no consensus as to whether antibiotics should be used perioperatively.

objectiveTo review the world literature and perform a meta-analysis of studies comparing wound infection rates with antibiotic use in breast reduction surgery.

methodsA literature search was performed using the MEDLINE, Cochrane Database of Systematic Reviews, Cochrane Database of Clinical Trials, Embase and CINAHL databases. Subject headings and relevant subheadings for "Breast", "Breast Reduction", "Reduction Mammaplasty", "Mammaplasty" were combined with "Antibiotics" and "Antibacterial Agents". The list of titles was assessed by the study's authors and abstracts were reviewed. All relevant articles were then independently reviewed by the two primary authors, and Jadad scoring was used to assess the quality of the included articles.

resultsFrom the original search, three randomized controlled trials were included in the meta-analysis of preoperative antibiotics. The meta-analysis revealed a 75% reduction in wound infections with preoperative antibiotics (OR 0.25 [95% CI 0.09 to 0.72]). Because only one randomized controlled trial analyzed postoperative antibiotics, no meta-analysis could be performed.

conclusionsPreoperative antibiotics should routinely be used before breast reduction surgery. The use of postoperative antibiotics remains controversial. Additional randomized studies investigating postoperative antibiotics are needed.

Indexed as

AntibioticsBreastMeta-analysisReduction mammoplastySurgical site infection

Identifiers

PMID25114620
PMCPMC4116322
OpenAlexW289210191

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.