ReviewIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion2014
Primary hepatic lymphoma: dilemmas in diagnostic approach and therapeutic management.
Review in Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 28 citations in OpenAlex.
- CT presentations of hepatic lymphoma: what radiologists need to know.Abdominal radiology (New York) · 2026Review
- Diffuse Large B-cell Lymphoma with Severe Lactic Acidosis and Liver Failure: A Case Report and Literature Review.Internal medicine (Tokyo, Japan) · 2025Review
- FDG PET-CT in Clinical Management of a Rare Case of Primary Hepatic Lymphoma: Role and Challenges.World journal of nuclear medicine · 2023Article
- Primary Hepatic Precursor B Lymphoblastic Lymphoma in a Toddler.Turkish archives of pediatrics · 2023Article
- Primary hepatic lymphoma of MALT type mimicking hepatic adenoma treated by hepatectomy: a case report and literature review.Frontiers in surgery · 2023Article
- Clinicopathologic Features of Lymphoproliferative Neoplasms Involving the Liver.Medicina (Kaunas, Lithuania) · 2022Article
- Primary hepatopancreatobiliary lymphoma: Pathogenesis, diagnosis, and management.Frontiers in oncology · 2022Review
- Primary hepatic lymphoma diagnosed using endoscopic ultrasound-guided liver biopsy: a case report.Journal of medical case reports · 2021Article
- Postsurgical Diagnosis of an Unusual Case of Primary Hepatic Lymphoma Presenting as Liver Abscess with an Uncommon Complication: A Hepatogastric Fistula.Case reports in hematology · 2021Article
- Diagnostic approach in hepatic lymphoma: radiological imaging findings and literature review.Journal of cancer research and clinical oncology · 2020Review
- [Primary diffuse large B-cell lymphoma in the liver: a case report].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2016Article
- Hypercalcemia due to Primary Hepatic Lymphoma.Case reports in hematology · 2016Article
- Primary hepatic lymphoma: features of a puzzling disease.Journal of gastrointestinal cancer · 2015Article
- Primary hepatic lymphoma in a patient with rheumatoid arthritis treated with methotrexate.Case reports in hematology · 2014Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary hepatic lymphoma (PHL) is a very rare malignancy and is characterized by liver involvement at presentation with no affectation of the spleen, lymph nodes, peripheral blood, bone marrow, or other tissues until at least 6 months after diagnosis. PHL should be considered in the differential diagnosis in a patient with space-occupying liver lesions and normal levels of alpha-fetoprotein and CEA. A computed tomography (CT) scan is the commonly used modality for staging lymphomas. The widespread use of positron emission tomography/CT results in the improvement in the accuracy of detecting the extent of disease, response evaluation, and prognostication. The liver biopsy, due to its pleomorphic appearances in the needle biopsy specimen, can be very challenging. Current literature favors the combination of chemotherapy as the frontline treatment for its least invasiveness and improved survival. Favorable prognosis of PHL can be obtained by early surgery combined with chemotherapy in strictly selected patients. However, the optimal therapy is still unclear and the outcomes are uncertain.
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