Evidence map›Paper›PMID 25113771›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2014

Role of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group.

Sally F Barrington, N George Mikhaeel, Lale Kostakoglu, Michel Meignan, Martin Hutchings, Stefan P Müeller, Lawrence H Schwartz, Emanuele Zucca, Richard I Fisher, Judith Trotman and 6 more

Erratum issued 3 registry-linked trialsOpen access · bronzeAbstract readConsensus Statement
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 3 registered trials, which are not on this map. Cited by 708 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
708citing papers in PubMed, 4 pooled it
95.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03973164 completednot on this mapstarted 2018, after this paper: background citation

Bone Marrow Cytology, Pathology and 18F-FDG PET/CT and Pelvic MRI in the Diagnosis of Lymphoma Bone Marrow Invasion

TypeobservationalSponsorGuangxi Medical UniversityRan2018 to 2019Enrolled142ConditionsLymphoma
NCT05343676 unknown statusnot on this mapstarted 2022, after this paper: background citation

Different Sonographic Modalities in Compared With PET-CT in Evaluation of Pediatric Lymphoma

TypeobservationalSponsorAssiut UniversityRan2022 to 2023Enrolled45ConditionsPediatric LymphomaArmsultrasonography
NCT06879340 phase1recruitingnot on this mapstarted 2025, after this paper: background citation

A Phase 1 Multicenter, Open Label Trial Evaluating the Safety and Efficacy of DuoCAR20.19.22-D95 in Adult Patients With Relapsed or Refractory B-cell Malignancies

TypeinterventionalSponsorUniversity of Kansas Medical CenterRan2025 to 2040Enrolled54ConditionsB-Cell Non-Hodgkin Lymphoma, B-cell Acute Lymphoblastic LeukemiaArmsDuoCAR20.19.22-D95, Fludarabine (Conditional therapy), Cyclophosphamide (Conditional therapy)
3 · Its place in the literature

Who cites it

708 citing papers in PubMed, 4 syntheses or guidelines pooled it, 1,615 citations in OpenAlex.

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648 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 7 countries.

Sally F Barrington
N George Mikhaeel
Lale Kostakoglu
Michel Meignan
Martin Hutchings
Stefan P Müeller
Lawrence H Schwartz
Emanuele Zucca
Richard I Fisher
Judith Trotman
Otto S Hoekstra
Rodney J Hicks
Michael J O'Doherty
Roland Hustinx
Alberto Biggi
Bruce D Cheson
Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo · ITCentre Hospitalier Universitaire Henri-Mondor · FRColumbia University Irving Medical Center · USKlinik und Poliklinik für Nuklearmedizin · DENational Health Service · GBOspedale San Giovanni Bellinzona · CHUniversity of Melbourne · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRecent advances in imaging, use of prognostic indices, and molecular profiling techniques have the potential to improve disease characterization and outcomes in lymphoma. International trials are under way to test image-based response–adapted treatment guided by early interim positron emission tomography (PET)–computed tomography (CT). Progress in imaging is influencing trial design and affecting clinical practice. In particular, a five-point scale to grade response using PET-CT, which can be adapted to suit requirements for early- and late-response assessment with good interobserver agreement, is becoming widely used both in practice- and response-adapted trials. A workshop held at the 11th International Conference on Malignant Lymphomas (ICML) in 2011 concluded that revision to current staging and response criteria was timely.

methodsAn imaging working group composed of representatives from major international cooperative groups was asked to review the literature, share knowledge about research in progress, and identify key areas for research pertaining to imaging and lymphoma.

resultsA working paper was circulated for comment and presented at the Fourth International Workshop on PET in Lymphoma in Menton, France, and the 12th ICML in Lugano, Switzerland, to update the International Harmonisation Project guidance regarding PET. Recommendations were made to optimize the use of PET-CT in staging and response assessment of lymphoma, including qualitative and quantitative methods.

conclusionThis article comprises the consensus reached to update guidance on the use of PET-CT for staging and response assessment for [18F]fluorodeoxyglucose-avid lymphomas in clinical practice and late-phase trials.

Indexed as

Fluorodeoxyglucose F18Positron-Emission TomographyRadiopharmaceuticalsTomography, X-Ray ComputedHumansInternational CooperationLymphomaNeoplasm StagingPredictive Value of TestsPrognosisTreatment OutcomeFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID25113771
PMCPMC5015423
OpenAlexW2131900456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.