ReviewJournal of clinical oncology : official journal of the American Society of Clinical Oncology2014
Cranial stereotactic radiosurgery: current status of the initial paradigm shifter.
Review in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Decision-making between DCA and VMAT in Linac-based SRS for brain lesions: A dosimetric analysis based on tumor size and geometry and introduction of Qasym.Journal of applied clinical medical physics · 2025Article
- Bridging the Beam Gap: Expanding Global Access to Stereotactic Radiosurgery Through Policy and Innovation.Cureus · 2025Article
- Article
- Adaptation of dose-prescription for vestibular schwannoma radiosurgery taking body contouring method and heterogeneous material into account.Acta oncologica (Stockholm, Sweden) · 2025Article
- Self-Shielding Gyroscopic Radiosurgery: A Prospective Experience and Analysis of the First 100 Patients.Cureus · 2024Article
- Stereotactic Ablative Brachytherapy: Recent Advances in Optimization of Radiobiological Cancer Therapy.Cancers · 2021Review
- Knowledge-based planning in robotic intracranial stereotactic radiosurgery treatments.Journal of applied clinical medical physics · 2021Article
- The evolution of stereotactic radiosurgery in neurosurgical practice.Journal of neuro-oncology · 2021Review
- Secondary malignancy following stereotactic radiosurgery for benign neurologic disease: A cohort study and review of the literature.Journal of radiosurgery and SBRT · 2020Article
- Focused Ultrasound and Other Lesioning Therapies in Movement Disorders.Current neurology and neuroscience reports · 2019Review
- Article
- Volumetric Modulated Arc (Radio) Therapy in Pets Treatment: The "La Cittadina Fondazione" Experience.Cancers · 2018Review
- Clinical efficacy and safety of surface imaging guided radiosurgery (SIG-RS) in the treatment of benign skull base tumors.Journal of neuro-oncology · 2017Article
- Simultaneous integrated protection : A new concept for high-precision radiation therapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2016Article
- Evaluation of the stability of the stereotactic Leksell Frame G in Gamma Knife radiosurgery.Journal of applied clinical medical physics · 2016Article
- The Rationale for Targeted Therapies and Stereotactic Radiosurgery in the Treatment of Brain Metastases.The oncologist · 2016Review
- National trends in inpatient admissions following stereotactic radiosurgery and the in-hospital patient outcomes in the United States from 1998 to 2011.Journal of radiosurgery and SBRT · 2016Article
- Current status of cranial stereotactic radiosurgery in the UK.The British journal of radiology · 2016Article
- Clinical outcomes of benign brain tumors treated with single fraction LINAC-based stereotactic radiosurgery: Experience of a single institute.Tzu chi medical journalArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The concept of stereotactic radiosurgery (SRS) was first described by Lars Leksell in 1951. It was proposed as a noninvasive alternative to open neurosurgical approaches to manage a variety of conditions. In the following decades, SRS emerged as a unique discipline involving a collegial partnership among neurosurgeons, radiation oncologists, and medical physicists. SRS relies on the precisely guided delivery of high-dose ionizing radiation to an intracranial target. The focused convergence of multiple beams yields a potent therapeutic effect on the target and a steep dose fall-off to surrounding structures, thereby minimizing the risk of collateral damage. SRS is typically administered in a single session but can be given in as many as five sessions or fractions. By providing an ablative effect noninvasively, SRS has altered the treatment paradigms for benign and malignant intracranial tumors, functional disorders, and vascular malformations. Literature on extensive intracranial radiosurgery has unequivocally demonstrated the favorable benefit-to-risk profile that SRS affords for appropriately selected patients. In a departure from conventional radiotherapeutic strategies, radiosurgical principles have recently been extended to extracranial indications such as lung, spine, and liver tumors. The paradigm shift resulting from radiosurgery continues to alter the landscape of related fields.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.