ReviewCurrent genetics2015
Stress response signaling and virulence: insights from entomopathogenic fungi.
Review in Current genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 69 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 171 citations in OpenAlex.
- Comparative mitochondrial genomics of Ophiocordycipitaceae fungi reveals AT bias and site-specific positive selection in the nad4 gene.Archives of microbiology · 2026Article
- Frontiers in fungal phosphatases: molecular diversity, regulatory mechanisms, analytical methodologies, ecological significance, and prospects for sustainable utilization.Frontiers in bioengineering and biotechnology · 2026Review
- Article
- MAPK Pathways Coordinate Stress Adaptation by Mobilizing Specialized Gene Modules in Entomopathogenic FungusJournal of fungi (Basel, Switzerland) · 2025Article
- Assessment of the antimicrobial efficacy of probiotics, biosynthesized silver nanoparticles, and their combination with physical irradiations against cattle endometritis pathogens.Scientific reports · 2025Article
- The regulatory network ofMicrobiology spectrum · 2025Article
- UV-Induced Mutants ofJournal of fungi (Basel, Switzerland) · 2025Article
- Fungal Stress Responses and the Importance of GPCRs.Journal of fungi (Basel, Switzerland) · 2025Review
- Development of Biphasic Culture System for an Entomopathogenic FungusJournal of fungi (Basel, Switzerland) · 2025Article
- Underlying the early signaling and gene expression of Pleurotus ostreatus mycelia during injury response.World journal of microbiology & biotechnology · 2025Article
- Genome Sequence, Comparative Genome Analysis, and Expression Profiling of the Chitinase GH18 Gene Family inInternational journal of molecular sciences · 2025Article
- Functional characterization of BbEaf6 inVirulence · 2024Article
- Exploring secretory signal sequences useful in excreting recombinant proteins in Beauveria bassiana as biocontrol fungus.Archives of microbiology · 2024Article
- Article
- Glyoxal oxidase-mediated detoxification of reactive carbonyl species contributes to virulence, stress tolerance, and development in a pathogenic fungus.PLoS pathogens · 2024Article
- Article
- Manipulating multi-level selection in a fungal entomopathogen reveals social conflicts and a method for improving biocontrol traits.PLoS pathogens · 2024Article
- Two sirtuin proteins, Hst3 and Hst4, modulate asexual development, stress tolerance, and virulence by affecting global gene expression inMicrobiology spectrum · 2024Article
- Fungal co-expression network analyses identify pathogen gene modules associated with host insect invasion.Microbiology spectrum · 2023Article
- TOR Signaling Tightly Regulated Vegetative Growth, Conidiation, Oxidative Stress Tolerance and Entomopathogenicity in the FungusMicroorganisms · 2023Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Ascomycete fungal insect pathogens, Beauveria and Metarhizium spp. have emerged as model systems with which to probe diverse aspects of fungal growth, stress response, and pathogenesis. Due to the availability of genomic resources and the development of robust methods for genetic manipulation, the last 5 years have witnessed a rapid increase in the molecular characterization of genes and their pathways involved in stress response and signal transduction in these fungi. These studies have been performed mainly via characterization of gene deletion/knockout mutants and have included the targeting of general proteins involved in stress response and/or virulence, e.g. catalases, superoxide dismutases, and osmolyte balance maintenance enzymes, membrane proteins and signaling pathways including GPI anchored proteins and G-protein coupled membrane receptors, MAPK pathways, e.g. (i) the pheromone/nutrient sensing, Fus3/Kss1, (ii) the cell wall integrity, Mpk1, and (iii) the high osmolarity, Hog1, the PKA/adenyl cyclase pathway, and various downstream transcription factors, e.g. Msn2, CreA and Pac1. Here, we will discuss current research that strongly suggests extensive underlying contributions of these biochemical and signaling pathways to both abiotic stress response and virulence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.