Evidence map›Paper›PMID 25113389›Full record

Trial reportCardiovascular ultrasound2014

3D Strain helps relating LV function to LV and structure in athletes.

Laura Stefani, Alessio De Luca, Loira Toncelli, Gianni Pedrizzetti, Giorgio Galanti

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Cardiovascular ultrasound, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Myocardial Fitness of Bicuspid Aortic Valve Athletes during COVID 19 Pandemic.Journal of functional morphology and kinesiology · 2022
    Article
  3. Article
  4. Observational
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  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Laura StefaniSport Medicine Center, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy. laura.stefani@unifi.it.
Alessio De Luca
Loira Toncelli
Gianni Pedrizzetti
Giorgio Galanti
University of Florence · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe evaluation of cardiac contraction could benefit from a connection with the underlying helical structure of cardiac fibers in athletes either completely healthy or with minor common cardiopathies like Bicuspid Aortic Valve (BAV). This study aims to exploit the potential role of 3D strain to improve the physiological understanding of LV function and modification due to physical activity as a comparative model.

methodsThree age-matched groups of young (age 20.3 ± 5.4) individuals are prospectively enrolled: 15 normal healthy subjects, 15 healthy athletes, and 20 athletes with bicuspid aortic valve (BAV). All subjects underwent echocardiographic examination and both 2D and 3D strain analysis.

resultsAll echo parameters were within the normal range in the three groups. Global values of end-systolic longitudinal and circumferential strain, assesses by either 2D or 3D analysis, were not significantly different. The 3D strain analysis was extended in terms of principal and secondary strain (PS, SS). Global PS was very similar, global SS was significantly higher in athletes and displays a modified time course. The comparative analysis of strain-lines pattern suggests that the enhancement of LV function is achieved by a more synchronous recruitment of both left- and right-handed helical fibers.

conclusions3D strain analysis allows a deeper physiological understanding of LV contraction in different types of athletes. Secondary strain, only available in 3D, identifies increase of performances due to physical activity; this appears to follow from the synergic activation of endocardial and epicardial fibers.

Indexed as

SportsVentricular Function, LeftAdultAortic ValveBicuspid Aortic Valve DiseaseEchocardiography, Three-DimensionalElasticity Imaging TechniquesElastic ModulusHeart Valve DiseasesHeart VentriclesHumansMaleReproducibility of ResultsSensitivity and SpecificityVentricular Dysfunction, Left

Identifiers

PMID25113389
PMCPMC4138416
OpenAlexW2139941951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.