Evidence map›Paper›PMID 25113318›Full record

ArticleArchives of women's mental health2014

Time trends of antidepressant drug prescriptions in men versus women in a geographically defined US population.

Wenjun Zhong, Hilal Maradit Kremers, Barbara P Yawn, William V Bobo, Jennifer L St Sauver, Jon O Ebbert, Lila J Finney Rutten, Debra J Jacobson, Scott M Brue, Walter A Rocca

Abstract read
In one paragraph

Article in Archives of women's mental health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Patterns of antidepressant prescribing around pregnancy: a descriptive analysis using Clinical Practice Research Datalink GOLD.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Conflict in Men's Experiences With Antidepressants.American journal of men's health · 2018
    Article
  15. Article
  16. Influences on antidepressant prescribing trends in the UK: 1995-2011.Social psychiatry and psychiatric epidemiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenjun ZhongGeneral Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA, zhongw@email.chop.edu.
Hilal Maradit Kremers
Barbara P Yawn
William V Bobo
Jennifer L St Sauver
Jon O Ebbert
Lila J Finney Rutten
Debra J Jacobson
Scott M Brue
Walter A Rocca

Funding

Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
NIA NIH HHS R01 AG034676NIA NIH HHS R01AG034676
6 · The paper itself

Abstract

The aim of this work was to study time trends of antidepressant drug (AD) prescriptions in a geographically defined US population between 2005 and 2011 for men and women separately. Using the Rochester Epidemiology Project medical records-linkage system, we identified all Olmsted County, MN residents who received AD outpatient prescriptions between 2005 and 2011 (7 years). We calculated the annual age- and sex-specific prevalence over 7 years and used generalized estimating equation models to test for time trends. The prevalence of subjects receiving at least one AD prescription was approximately two times higher in women than in men consistently across the 7 years of the study. The standardized annual prevalence increased from 10.8 % in 2005 to 14.4 % in 2011 overall, from 7.0 % in 2005 to 9.9 % in 2011 for men, and from 14.4 % in 2005 to 18.6 % in 2011 for women. The absolute percent increase was greater in women (4.2 vs. 2.9 %; standardized); however, the relative percent increase was greater in men (41.4 vs. 29.2 %; standardized). The relative percent increase was greater in the age group 65+ years for both men and women. AD prescriptions are increasing over time, especially in the elderly. Women receive more AD prescriptions than men. However, the relative increase in AD prescriptions over time is greater in men than women.

Indexed as

AgedAged, 80 and overAge DistributionAntidepressive AgentsDepressionDrug PrescriptionsDrug UtilizationFemaleHumansMaleMiddle AgedPrescriptionsPrevalenceSex DistributionSex FactorsUnited StatesAntidepressive Agents

Identifiers

PMID25113318
PMCPMC4239307

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.