Evidence map›Paper›PMID 25112941›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2015

Relationship between cervical sagittal alignment and quality of life in ankylosing spondylitis.

Jung Sub Lee, Myung Soo Youn, Jong Ki Shin, Tae Sik Goh, Sung Shik Kang

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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Sagittal balance of the cervical spine: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Pooled it
  2. Guideline
  3. Which parameters are relevant in sagittal balance analysis of the cervical spine? A literature review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018
    Pooled it
  4. Article
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  8. Neck and shoulder pain in thoracic adolescent idiopathic scoliosis 10 years after posterior spinal fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
  9. Article
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  15. Health-related quality of life in patients undergoing cervico-thoracic osteotomies for fixed cervico-thoracic kyphosis in patients with ankylosing spondylitis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018
    Article
  16. Review
  17. Osteotomies in ankylosing spondylitis: where, how many, and how much?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018
    Review
  18. The change of cervical spine alignment along with aging in asymptomatic population: a preliminary analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017
    Article
  19. CORR InsightsClinical orthopaedics and related research · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jung Sub LeeDepartment of Orthopaedic Surgery, Medical Research Institute, Pusan National University School of Medicine, 1-10 Ami-Dong, Seo-Gu, Busan, 602-739, Republic of Korea, jungsublee@pusan.ac.kr.
Myung Soo Youn
Jong Ki Shin
Tae Sik Goh
Sung Shik Kang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLittle information is available on the relationship between cervical sagittal alignment and health-related quality of life (HRQOL) in ankylosing spondylitis (AS) patients. The aim of this study was to identify relationships between cervical sagittal alignment and HRQOL in AS.

methodsThe study and control groups comprised 102 AS patients (15 women and 87 men) and age- and sex-matched 50 controls, respectively. All underwent anteroposterior and lateral radiographs and completed clinical questionnaires. The radiographic parameters examined were C2-C7 lordosis, C2-C7 sagittal vertical axis (SVA), T1 slope and T1 slope minus C2-C7 lordosis (TS-CL). A visual analogue scale (VAS 0-10) score for neck pain, the neck disability index (NDI), neck pain and disability (NPAD) scale and bath ankylosing spondylitis disease activity index (BASDAI) were administered to evaluate QOL. Statistical analysis was performed to determine the significances of differences between the study and control groups. In addition, correlations between radiological parameters and clinical questionnaires were sought.

resultsAS patients and controls were found to be different significantly in terms of C2-C7 SVA, T1 slope, and TS-CL. However, no significant intergroup difference was observed for C2-C7 lordosis (P > 0.05). Correlation analysis revealed significant relationships between radiographic parameters and QOL. Multiple regression analysis was performed to identify predictors of QOL, and the results obtained revealed that C2-C7 SVA significantly predicted VAS, NDI, and NPAD scores and that age predicted NPAD score.

conclusionsCervical sagittal parameters were found to be significantly different in AS patients and normal controls. Correlation analysis revealed significant relationships between radiographic parameters and QOL. In particular, C2-C7 SVA was found to be a significant predictor of QOL in AS patient.

Indexed as

Quality of LifeAdultCase-Control StudiesCervical VertebraeFemaleHumansLordosisMaleMiddle AgedNeck PainPain MeasurementProspective StudiesRadiographyRegression AnalysisSpondylitis, AnkylosingSurveys and Questionnaires

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.