Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2015
Incidence and predictors of anticipatory nausea and vomiting in Asia Pacific clinical practice--a longitudinal analysis.
Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06485869 (Impact of Virtual Reality on the Quality of Life of Oncology Patients), which is not on this map. Cited by 15 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Virtual Reality on the Quality of Life of Oncology Patients
Who cites it
15 citing papers in PubMed.
- Trial
- A randomized trial of nurse-administered behavioral interventions to manage anticipatory nausea and vomiting in chemotherapy.Cancer medicine · 2020Trial
- Risk factors associated with anticipatory nausea and vomiting in children receiving chemotherapy: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Factors influencing the hope of patients with advanced cancer while receiving cancer pharmacotherapy.Japan journal of nursing science : JJNS · 2025Article
- Risk factors of nausea and vomiting in patients with breast cancer undergoing chemotherapy: A retrospective study.Medicine · 2025Observational
- Article
- Prevalence of anticipatory nausea and vomiting in breast cancer patients undergoing highly emetogenic chemotherapy.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Psychological predictors of chemotherapy-induced nausea in women with breast cancer: Expectancies and perceived susceptibility.European journal of cancer care · 2021Article
- Article
- Applicability of the National Comprehensive Cancer Network/Multinational Association of Supportive Care in Cancer Guidelines for Prevention and Management of Chemotherapy-Induced Nausea and Vomiting in Southeast Asia: A Consensus Statement.Journal of global oncology · 2017Article
- 2016 updated MASCC/ESMO consensus recommendations: Anticipatory nausea and vomiting in children and adults receiving chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017Article
- Clinical Practices and Outcomes on Chemotherapy-Induced Nausea and Vomiting Management in South Korea: Comparison with Asia-Pacific Data of the Pan Australasian Chemotherapy Induced Emesis Burden of Illness Study.Cancer research and treatment · 2016Article
- Article
- Impact of CINV in earlier cycles on CINV and chemotherapy regimen modification in subsequent cycles in Asia Pacific clinical practice.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015Article
- Rationale and design of the Pan Australasian chemotherapy-induced emesis burden of illness study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015Observational
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSome patients experience nausea and/or vomiting (NV) before receipt of chemotherapy. Our objective was to evaluate the impact of prior chemotherapy-induced NV (CINV) on the incidence of anticipatory NV in later cycles.
methodsThis multicenter, prospective non-interventional study enrolled chemotherapy-naïve adults scheduled to receive highly or moderately emetogenic chemotherapy (HEC/MEC) for cancer in six Asia Pacific countries, excluding those with emesis within 24 h before cycle 1 chemotherapy. On day 1 before chemotherapy, patients answered four questions regarding emesis in the past 24 h, nausea, expectation of post-chemotherapy nausea, and anxiety in the past 24 h, the latter three scored from 0-10 (none-maximum). Multivariate logistic regression was used to assess the impact of prior CINV on anticipatory NV in cycles 2 and 3.
resultsFive hundred ninety-eight patients (59% female) were evaluable in cycle 2 (49% HEC, 51% MEC). The incidence of anticipatory emesis was low before cycles 2 and 3 (1.5-2.3%). The incidence of clinically significant anticipatory nausea (score of ≥3) was 4.8, 7.9, and 8.3% before cycles 1, 2, and 3, respectively, with adjusted odds ratio (OR), 3.95 (95% confidence interval (CI), 2.23-7.00; p < 0.001) for patients with clinically significant nausea in prior cycles, compared with none. The adjusted ORs for other anticipatory NV endpoints ranged from 4.54-4.74 for patients with prior CINV. The occurrence of clinically significant anxiety in the prior cycle also resulted in a significantly increased likelihood of anticipatory nausea.
conclusionsThese findings highlight the importance of preventing CINV in cycle 1 to reduce anticipatory NV in subsequent cycles.
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