Evidence map›Paper›PMID 25112307›Full record

Trial reportJournal of neurology, neurosurgery, and psychiatry2015

Brief intervention for medication-overuse headache in primary care. The BIMOH study: a double-blind pragmatic cluster randomised parallel controlled trial.

Espen Saxhaug Kristoffersen, Jørund Straand, Kjersti Grøtta Vetvik, Jūratė Šaltytė Benth, Michael Bjørn Russell, Christofer Lundqvist

2 registry-linked trialsOpen access · hybridAbstract readPragmatic Clinical TrialRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of neurology, neurosurgery, and psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 47 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 3 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01314768 nacompletednot on this map

RCT of Structured Brief Intervention for Medication Overuse Headache Versus Business as Usual

TypeinterventionalSponsorUniversity Hospital, AkershusRan2011 to 2013Enrolled123ConditionsMedication-overuse Headache, Chronic HeadacheArmsBrief intervention, Business as usual, Screening and outcome evaluation only
NCT06032715 narecruitingnot on this mapstarted 2023, after this paper: background citation

Brief Intervention for Reducing Prolonged Use of Sleep Medication Among Elderly

TypeinterventionalSponsorUniversity Hospital, AkershusRan2023 to 2025Enrolled120ConditionsHarmful Use of HypnoticArmsBI (Brief Intervention)
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 97 citations in OpenAlex.

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  14. GPs' experiences with brief intervention for medication-overuse headache: a qualitative study in general practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014
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  19. Novel motivational interviewing-based intervention improves engagement in physical activity and readiness to change among adolescents with chronic pain.Health expectations : an international journal of public participation in health care and health policy · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Espen Saxhaug KristoffersenDepartment of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway HØKH, Research Centre, Akershus University Hospital, Lørenskog, Norway.
Jørund StraandDepartment of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway.
Kjersti Grøtta VetvikHead and Neck Research Group, Research Centre, Akershus University Hospital, Lørenskog, Norway Institute of Clinical Medicine, Campus Akershus University Hospital, University of Oslo, Nordbyhagen, Norway Department of Neurology, Akershus University Hospital, Nordbyhagen, Norway.
Jūratė Šaltytė BenthHØKH, Research Centre, Akershus University Hospital, Lørenskog, Norway Institute of Clinical Medicine, Campus Akershus University Hospital, University of Oslo, Nordbyhagen, Norway.
Michael Bjørn RussellHead and Neck Research Group, Research Centre, Akershus University Hospital, Lørenskog, Norway Institute of Clinical Medicine, Campus Akershus University Hospital, University of Oslo, Nordbyhagen, Norway.
Christofer LundqvistHØKH, Research Centre, Akershus University Hospital, Lørenskog, Norway Institute of Clinical Medicine, Campus Akershus University Hospital, University of Oslo, Nordbyhagen, Norway Department of Neurology, Akershus University Hospital, Nordbyhagen, Norway.
University of Oslo · NOAkershus University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedication-overuse headache (MOH) is common in the general population. We investigated effectiveness of brief intervention (BI) for achieving drug withdrawal in primary care patients with MOH.

methodsThe study was double-blind, pragmatic and cluster-randomised controlled. A total of 25,486 patients (age 18-50) from 50 general practitioners (GPs) were screened for MOH. GPs defined clusters and were randomised to receive BI training (23 GPs) or to continue business as usual (BAU; 27 GPs). The Severity of Dependence Scale was applied as a part of the BI. BI involved feedback about individual risk of MOH and how to reduce overuse. Primary outcome measures were reduction in medication and headache days/month 3 months after the intervention and were assessed by a blinded clinical investigator.

results42% responded to the postal screening questionnaire, and 2.4% screened positive for MOH. A random selection of up to three patients with MOH from each GP were invited (104 patients), 75 patients were randomised and 60 patients included into the study. BI was significantly better than BAU for the primary outcomes (p<0.001). Headache and medication days were reduced by 7.3 and 7.9 (95% CI 3.2 to 11.3 and 3.2 to 12.5) days/month in the BI compared with the BAU group. Chronic headache resolved in 50% of the BI and 6% of the BAU group.

conclusionsThe BI method provides GPs with a simple and effective instrument that reduces medication-overuse and headache frequency in patients with MOH. TRIAL REGISTRATION NUMBER: NCT01314768.

Indexed as

Primary Health CarePsychotherapy, BriefAdolescentAdultAnalgesicsDouble-Blind MethodFemaleHeadache Disorders, SecondaryHumansMaleSubstance-Related DisordersTreatment OutcomeYoung AdultAnalgesicsHEADACHEMIGRAINEPAIN

Identifiers

PMID25112307
PMCPMC4413802
OpenAlexW2148786262

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.