ReviewCurrent opinion in otolaryngology & head and neck surgery2014
Noise-induced hearing loss: new animal models.
Review in Current opinion in otolaryngology & head and neck surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- A nonneural miRNA cluster mediates hearing via repression of two neural targets.Genes & development · 2023Article
- Impact of noise on development, physiological stress and behavioural patterns in larval zebrafish.Scientific reports · 2021Article
- Physiological Basis of Noise-Induced Hearing Loss in a Tympanal Ear.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Otoprotective Effects of Stephania tetrandra S. Moore Herb Isolate against Acoustic Trauma.Journal of the Association for Research in Otolaryngology : JARO · 2018Article
- Hearing in Drosophila.Current opinion in neurobiology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
purpose of the reviewThis article presents research findings from two invertebrate model systems with potential to advance both the understanding of noise-induced hearing loss mechanisms and the development of putative therapies to reduce human noise damage. RECENT
findingsWork on sea anemone hair bundles, which resemble auditory hair cells, has revealed secretions that exhibit astonishing healing properties not only for damaged hair bundles, but also for vertebrate lateral line neuromasts. We present progress on identifying functional components of the secretions, and their mechanisms of repair. The second model, the Johnston's organ in Drosophila, is also genetically homologous to hair cells and shows noise-induced hearing loss similar to vertebrates. Drosophila offers genetic and molecular insight into noise sensitivity and pathways that can be manipulated to reduce stress and damage from noise. SUMMARY: Using the comparative approach is a productive avenue to understanding basic mechanisms, in this case cellular responses to noise trauma. Expanding study of these systems may accelerate identification of strategies to reduce or prevent noise damage in the human ear.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.