Evidence map›Paper›PMID 25110721›Full record

ArticleJournal of neurology and psychology2013

Biomarker Development for Brain-Based Disorders: Recent Progress in Psychiatry.

James O Ebot Enaw, Alicia K Smith

Abstract read
In one paragraph

Article in Journal of neurology and psychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Data mining EEG signals in depression for their diagnostic value.BMC medical informatics and decision making · 2015
    Article
  5. DNA extracted from saliva for methylation studies of psychiatric traits: evidence tissue specificity and relatedness to brain.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

James O Ebot EnawDepartment of Psychiatry & Behavioral Sciences, Emory University, School of Medicine, Atlanta, GA, USA.
Alicia K SmithDepartment of Psychiatry & Behavioral Sciences, Emory University, School of Medicine, Atlanta, GA, USA.

Funding

Genetic & Environmental Risk Factors that Contribute to Childhood PsychopathologyK01MH085806 · NIMH · EMORY UNIVERSITY · PI SMITH, ALICIA K · 2010 to 2013
$522k
NIMH NIH HHS K01 MH085806
6 · The paper itself

Abstract

Biomarkers are biological measures that are indicative of a specific disorder, its severity or response to treatment. They are widely used in many areas of medicine, but biomarker development for brain-based disorders lags behind. Using examples from the field of psychiatry, this article reviews the concepts of biomarkers, challenges to their development and the recent progress along those lines. In addition to discussing historical biomarker candidates such as cortisol or catecholamine levels, we include progress from recent genetic, epigenetic, proteomic, neuroimaging and EEG studies. Successful identification of biomarkers will advance the field of psychiatry towards the goal of biological tests for diagnosis, symptom management and treatment response.

Indexed as

BDNFBiomarkerBrainCortisolGeneticNeuroimagingPsychiatryPsychology

Identifiers

PMID25110721
PMCPMC4123758

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.