Evidence map›Paper›PMID 25110708›Full record

ReviewBioMed research international2014

A review on the traditional Chinese medicinal herbs and formulae with hypolipidemic effect.

Tung-Ting Sham, Chi-On Chan, You-Hua Wang, Jian-Mei Yang, Daniel Kam-Wah Mok, Shun-Wan Chan

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
10.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 115 citations in OpenAlex.

  1. Ameliorative Effects ofFoods (Basel, Switzerland) · 2026
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  4. Review
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  6. Article
  7. Article
  8. Hypolipidemic and Antihyperlipidemic Effects ofLife (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. In Silico Network Analysis of Ingredients of Cornus officinalis in Osteoporosis.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Article
  18. Complex natural product production methods and options.Synthetic and systems biotechnology · 2021
    Review
  19. Safety of high-doseFood science & nutrition · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Tung-Ting ShamDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong.
Chi-On ChanDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong ; State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), Shenzhen 518057, China.
You-Hua WangLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Jian-Mei YangXuhui District Central Hospital of Shanghai, Shanghai 200031, China.
Daniel Kam-Wah MokDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong ; State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), Shenzhen 518057, China.
Shun-Wan ChanDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong ; State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), Shenzhen 518057, China ; Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong.
Hong Kong Polytechnic University · HKLonghua Hospital Shanghai University of Traditional Chinese Medicine · CNShanghai Xuhui Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperlipidemia, characterized by the abnormal blood lipid profiles, is one of the dominant factors of many chronic diseases such as diabetes, obesity, and cardiovascular diseases (CVD). For the low cost, effectiveness, and fewer side effects, the popularity of using traditional Chinese medicine (TCM) to handle hyperlipidemia is increasing and its role in health care has been recognized by the public at large. Despite the importance of TCM herbs and formulations, there is no comprehensive review summarizing their scientific findings on handling hyperlipidemia. This review summarizes the recent experimental and clinical results of nine representative single Chinese herbs and seven classic TCM formulae that could improve lipid profiles so as to help understand and compare their underlying mechanisms. Most of single herbs and formulae demonstrated the improvement of hyperlipidemic conditions with multiple and diverse mechanisms of actions similar to conventional Western drugs in spite of their mild side effects. Due to increasing popularity of TCM, more extensive, well-designed preclinical and clinical trials on the potential synergistic and adverse side effects of herb-drug interactions as well as their mechanisms are warranted. Hyperlipidemic patients should be warned about the potential risks of herb-drug interactions, particularly those taking anticoagulants and antiplatelet drugs.

Indexed as

Plants, MedicinalClinical Trials as TopicDrugs, Chinese HerbalHumansHyperlipidemiasHypolipidemic AgentsMedicine, Chinese TraditionalDrugs, Chinese HerbalHypolipidemic Agents

Identifiers

PMID25110708
PMCPMC4109135
OpenAlexW1987626083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.