Evidence map›Paper›PMID 25110612›Full record

ReviewAging and disease2014

Nothobranchius as a model for aging studies. A review.

Alejandro Lucas-Sánchez, Pedro Francisco Almaida-Pagán, Pilar Mendiola, Jorge de Costa

Abstract readReview
In one paragraph

Review in Aging and disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. The Effect of Meclofenoxate on the Transcriptome of Aging Brain ofInternational journal of molecular sciences · 2022
    Article
  4. Membrane lipids and maximum lifespan in clownfish.Fish physiology and biochemistry · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alejandro Lucas-SánchezDepartment of Physiology. Faculty of Biology. University of Murcia. 30100 Murcia, Spain.
Pedro Francisco Almaida-PagánInstitute of Aquaculture, School of Natural Sciences, University of Stirling, Stirling FK9 4LA, UK.
Pilar MendiolaDepartment of Physiology. Faculty of Biology. University of Murcia. 30100 Murcia, Spain.
Jorge de CostaDepartment of Physiology. Faculty of Biology. University of Murcia. 30100 Murcia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent decades, the increase in human longevity has made it increasingly important to expand our knowledge on aging. To accomplish this, the use of animal models is essential, with the most common being mouse (phylogenetically similar to humans, and a model with a long life expectancy) and Caenorhabditis elegans (an invertebrate with a short life span, but quite removed from us in evolutionary terms). However, some sort of model is needed to bridge the differences between those mentioned above, achieving a balance between phylogenetic distance and life span. Fish of the genus Nothobranchius were suggested 10 years ago as a possible alternative for the study of the aging process. In the meantime, numerous studies have been conducted at different levels: behavioral (including the study of the rest-activity rhythm), populational, histochemical, biochemical and genetic, among others, with very positive results. This review compiles what we know about Nothobranchius to date, and examines its future prospects as a true alternative to the classic models for studies on aging.

Indexed as

AgingFishkillifishNothobranchius

Identifiers

PMID25110612
PMCPMC4113518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.