ArticleInternational journal of endocrinology2014
Serum 25-OH Vitamin D in relation to Bone Mineral Density and Bone Turnover.
Article in International journal of endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Prediction model for low bone mass mineral density in type 2 diabetes: an observational cross-sectional study.Endocrine · 2024Observational
- Article
- Serum 25-Hydroxyvitamin D is Associated With Bone Microarchitecture and Strength in a Multiracial Cohort of Young Adults.The Journal of clinical endocrinology and metabolism · 2022Article
- The Effect of Selected Herbal Medicines on Bone Turnover Markers: A Systematic Review and Meta-Analysis.Journal of family & reproductive health · 2022Review
- Association between population vitamin D status and SARS-CoV-2 related serious-critical illness and deaths: An ecological integrative approach.World journal of virology · 2021Article
- Vitamin D Levels Are Reduced at the Time of Hospital Admission in Sicilian SARS-CoV-2-Positive Patients.International journal of environmental research and public health · 2021Article
- Article
- The Association of Vitamin D Status with Lipid Profile and Inflammation Biomarkers in Healthy Adolescents.Nutrients · 2020Article
- Serum 25-hydroxyvitamin D and bone turnover markers in Palestinian postmenopausal osteoporosis and normal women.Archives of osteoporosis · 2017Article
- Evaluation of fracture risk in chronic kidney disease.Journal of nephrology · 2017Review
- Article
- Vitamin D Status and Its Association with Parathyroid Hormone Concentration in Brazilians.Journal of nutrition and metabolism · 2017Article
- Hypovitaminosis D Among Patients Admitted With Hip Fracture to a Level-1 Trauma Center in the Sunny Upper Egypt: Prevalence and Associated Correlates.Geriatric orthopaedic surgery & rehabilitation · 2016Article
- Postmenopausal Breast Cancer, Aromatase Inhibitors, and Bone Health: What the Surgeon Should Know.World journal of surgery · 2016Review
- A Review of Cutoffs for Nutritional Biomarkers.Advances in nutrition (Bethesda, Md.) · 2016Review
- Serum Chemerin Levels in relation to Osteoporosis and Bone Mineral Density: A Case-Control Study.Disease markers · 2015Observational
- Risk factors of osteoporosis in soldiers of the Armed Forces: A cross-sectional study from Western India.Medical journal, Armed Forces IndiaArticle
- Relationship of vitamin D with bone mineral density, fracture type and social deprivation in neck of femur fractures.Journal of orthopaedicsArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is unclear which vitamin D status is optimal for bone health. In this study, we aimed to assess cutoffs of 25-hydroxyvitamin D (25OHD) derived by the literature (20, 25, or 30 ng/mL) in relation to bone turnover and bone mineral density (BMD). Serum 25OHD, PTH, osteocalcin, bone alkaline phosphatase, and C-telopeptide were measured in 274 consecutive postmenopausal women. BMD of the lumbar spine (L1-L4) and of femoral neck were also evaluated. 50 patients had normal BMD, while 124 had osteopenia and 100 had osteoporosis. 37.6%, 56.2%, and 70.8% subjects had serum 25OHD lower than 20, 25, or 30 ng/mL, respectively. No differences in bone turnover markers were found when comparing patients with low 25OHD defined according to the different cutoffs. However, a cutoff of 25 ng/mL appeared to differentiate better than a cutoff of 30 ng/mL in those subjects with reduced femoral neck BMD. The PTH plateau occurred at 25OHD levels of 26-30 ng/mL. In conclusion, vitamin D deficiency is common in Sicilian postmenopausal women and it may be associated with low BMD and increased bone turnover markers. Further studies are needed to better define the right cutoff for normal vitamin D levels in postmenopausal women.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.