Evidence map›Paper›PMID 25110428›Full record

ReviewWorld journal of gastroenterology2014

Liver metastases: Contrast-enhanced ultrasound compared with computed tomography and magnetic resonance.

Vito Cantisani, Hektor Grazhdani, Cristina Fioravanti, Maria Rosignuolo, Fabrizio Calliada, Daniela Messineo, Maria Giulia Bernieri, Adriano Redler, Carlo Catalano, Ferdinando D'Ambrosio

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Imaging the hallmarks of cancer.Nature reviews. Cancer · 2026
    Review
  2. Article
  3. Navigated hepatic tumor resection using intraoperative ultrasound imaging.International journal of computer assisted radiology and surgery · 2026
    Article
  4. Article
  5. Medullary Thyroid Carcinoma: Imaging.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Abdominal ultrasound in head and neck squamous cell carcinoma staging: yes or no?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
  11. Review
  12. Article
  13. Imaging of Colorectal Liver Metastasis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Endoscopic ultrasound in chronic liver disease.World journal of hepatology · 2020
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vito CantisaniVito Cantisani, Hektor Grazhdani, Cristina Fioravanti, Maria Rosignuolo, Daniela Messineo, Maria Giulia Bernieri, Adriano Redler, Carlo Catalano, Ferdinando D'Ambrosio, Department of Radiology, Oncology and Anatomo-Pathology "Sapienza" University of Rome, 00161 Rome, Italy.
Hektor GrazhdaniVito Cantisani, Hektor Grazhdani, Cristina Fioravanti, Maria Rosignuolo, Daniela Messineo, Maria Giulia Bernieri, Adriano Redler, Carlo Catalano, Ferdinando D'Ambrosio, Department of Radiology, Oncology and Anatomo-Pathology "Sapienza" University of Rome, 00161 Rome, Italy.
Cristina FioravantiVito Cantisani, Hektor Grazhdani, Cristina Fioravanti, Maria Rosignuolo, Daniela Messineo, Maria Giulia Bernieri, Adriano Redler, Carlo Catalano, Ferdinando D'Ambrosio, Department of Radiology, Oncology and Anatomo-Pathology "Sapienza" University of Rome, 00161 Rome, Italy.
Maria RosignuoloVito Cantisani, Hektor Grazhdani, Cristina Fioravanti, Maria Rosignuolo, Daniela Messineo, Maria Giulia Bernieri, Adriano Redler, Carlo Catalano, Ferdinando D'Ambrosio, Department of Radiology, Oncology and Anatomo-Pathology "Sapienza" University of Rome, 00161 Rome, Italy.
Fabrizio CalliadaVito Cantisani, Hektor Grazhdani, Cristina Fioravanti, Maria Rosignuolo, Daniela Messineo, Maria Giulia Bernieri, Adriano Redler, Carlo Catalano, Ferdinando D'Ambrosio, Department of Radiology, Oncology and Anatomo-Pathology "Sapienza" University of Rome, 00161 Rome, Italy.
Daniela MessineoVito Cantisani, Hektor Grazhdani, Cristina Fioravanti, Maria Rosignuolo, Daniela Messineo, Maria Giulia Bernieri, Adriano Redler, Carlo Catalano, Ferdinando D'Ambrosio, Department of Radiology, Oncology and Anatomo-Pathology "Sapienza" University of Rome, 00161 Rome, Italy.
Maria Giulia BernieriVito Cantisani, Hektor Grazhdani, Cristina Fioravanti, Maria Rosignuolo, Daniela Messineo, Maria Giulia Bernieri, Adriano Redler, Carlo Catalano, Ferdinando D'Ambrosio, Department of Radiology, Oncology and Anatomo-Pathology "Sapienza" University of Rome, 00161 Rome, Italy.
Adriano RedlerVito Cantisani, Hektor Grazhdani, Cristina Fioravanti, Maria Rosignuolo, Daniela Messineo, Maria Giulia Bernieri, Adriano Redler, Carlo Catalano, Ferdinando D'Ambrosio, Department of Radiology, Oncology and Anatomo-Pathology "Sapienza" University of Rome, 00161 Rome, Italy.
Carlo CatalanoVito Cantisani, Hektor Grazhdani, Cristina Fioravanti, Maria Rosignuolo, Daniela Messineo, Maria Giulia Bernieri, Adriano Redler, Carlo Catalano, Ferdinando D'Ambrosio, Department of Radiology, Oncology and Anatomo-Pathology "Sapienza" University of Rome, 00161 Rome, Italy.
Ferdinando D'AmbrosioVito Cantisani, Hektor Grazhdani, Cristina Fioravanti, Maria Rosignuolo, Daniela Messineo, Maria Giulia Bernieri, Adriano Redler, Carlo Catalano, Ferdinando D'Ambrosio, Department of Radiology, Oncology and Anatomo-Pathology "Sapienza" University of Rome, 00161 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of ultrasound contrast agents with excellent tolerance and safety profiles has notably improved liver evaluation with ultrasound (US) for several applications, especially for the detection of metastases. In particular, contrast enhanced ultrasonography (CEUS) allows the display of the parenchymal microvasculature, enabling the study and visualization of the enhancement patterns of liver lesions in real time and in a continuous manner in all vascular phases, which is similar to contrast-enhanced computed tomography (CT) and contrast-enhanced magnetic resonance imaging. Clinical studies have reported that the use of a contrast agent enables the visualization of more metastases with significantly improved sensitivity and specificity compared to baseline-US. Furthermore, studies have shown that CEUS yields sensitivities comparable to CT. In this review, we describe the state of the art of CEUS for detecting colorectal liver metastases, the imaging features, the literature reports of metastases in CEUS as well as its technique, its clinical role and its potential applications. Additionally, the updated international consensus panel guidelines are reported in this review with the inherent limitations of this technique and best practice experiences.

Indexed as

Contrast MediaMagnetic Resonance ImagingTomography, X-Ray ComputedHumansLiver NeoplasmsPredictive Value of TestsPrognosisUltrasonographyContrast Media18F-fluorodeoxyglucose positron emission tomographyColorectal cancerColorectal liver metastasesComputed tomographyContrast enhanced ultrasoundIntraoperative ultrasoundMagnetic resonance imagingUltrasoundUltrasound contrast agent

Identifiers

PMID25110428
PMCPMC4123379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.