Evidence map›Paper›PMID 25110422›Full record

ArticleWorld journal of gastroenterology2014

Helicobacter pylori and oral pathology: relationship with the gastric infection.

Isabel Adler, Andrea Muiño, Silvia Aguas, Laura Harada, Mariana Diaz, Adriana Lence, Mario Labbrozzi, Juan Manuel Muiño, Boris Elsner, Alejandra Avagnina and 1 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 6 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 6 syntheses or guidelines pooled it, 93 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Recurrent aphthous stomatitis and Helicobacter pylori.Medicina oral, patologia oral y cirugia bucal · 2016
    Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Article
  11. Diagnostics (Basel, Switzerland) · 2026
    Article
  12. BeyondMedicina (Kaunas, Lithuania) · 2025
    Review
  13. Article
  14. Comparative molecular detection ofIranian journal of microbiology · 2025
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Analysis of Genetic Relatedness between Gastric and OralInternational journal of molecular sciences · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Isabel AdlerIsabel Adler, Andrea Muiño, Silvia Aguas, Laura Harada, Mariana Diaz, Adriana Lence, Mario Labbrozzi, Juan Manuel Muiño, Oral Diseases Curriculum, School of Dentistry, University of Buenos Aires, C1053ABJ Buenos Aires, Argentina.
Andrea MuiñoIsabel Adler, Andrea Muiño, Silvia Aguas, Laura Harada, Mariana Diaz, Adriana Lence, Mario Labbrozzi, Juan Manuel Muiño, Oral Diseases Curriculum, School of Dentistry, University of Buenos Aires, C1053ABJ Buenos Aires, Argentina.
Silvia AguasIsabel Adler, Andrea Muiño, Silvia Aguas, Laura Harada, Mariana Diaz, Adriana Lence, Mario Labbrozzi, Juan Manuel Muiño, Oral Diseases Curriculum, School of Dentistry, University of Buenos Aires, C1053ABJ Buenos Aires, Argentina.
Laura HaradaIsabel Adler, Andrea Muiño, Silvia Aguas, Laura Harada, Mariana Diaz, Adriana Lence, Mario Labbrozzi, Juan Manuel Muiño, Oral Diseases Curriculum, School of Dentistry, University of Buenos Aires, C1053ABJ Buenos Aires, Argentina.
Mariana DiazIsabel Adler, Andrea Muiño, Silvia Aguas, Laura Harada, Mariana Diaz, Adriana Lence, Mario Labbrozzi, Juan Manuel Muiño, Oral Diseases Curriculum, School of Dentistry, University of Buenos Aires, C1053ABJ Buenos Aires, Argentina.
Adriana LenceIsabel Adler, Andrea Muiño, Silvia Aguas, Laura Harada, Mariana Diaz, Adriana Lence, Mario Labbrozzi, Juan Manuel Muiño, Oral Diseases Curriculum, School of Dentistry, University of Buenos Aires, C1053ABJ Buenos Aires, Argentina.
Mario LabbrozziIsabel Adler, Andrea Muiño, Silvia Aguas, Laura Harada, Mariana Diaz, Adriana Lence, Mario Labbrozzi, Juan Manuel Muiño, Oral Diseases Curriculum, School of Dentistry, University of Buenos Aires, C1053ABJ Buenos Aires, Argentina.
Juan Manuel MuiñoIsabel Adler, Andrea Muiño, Silvia Aguas, Laura Harada, Mariana Diaz, Adriana Lence, Mario Labbrozzi, Juan Manuel Muiño, Oral Diseases Curriculum, School of Dentistry, University of Buenos Aires, C1053ABJ Buenos Aires, Argentina.
Boris ElsnerIsabel Adler, Andrea Muiño, Silvia Aguas, Laura Harada, Mariana Diaz, Adriana Lence, Mario Labbrozzi, Juan Manuel Muiño, Oral Diseases Curriculum, School of Dentistry, University of Buenos Aires, C1053ABJ Buenos Aires, Argentina.
Alejandra AvagninaIsabel Adler, Andrea Muiño, Silvia Aguas, Laura Harada, Mariana Diaz, Adriana Lence, Mario Labbrozzi, Juan Manuel Muiño, Oral Diseases Curriculum, School of Dentistry, University of Buenos Aires, C1053ABJ Buenos Aires, Argentina.
Valeria DenninghoffIsabel Adler, Andrea Muiño, Silvia Aguas, Laura Harada, Mariana Diaz, Adriana Lence, Mario Labbrozzi, Juan Manuel Muiño, Oral Diseases Curriculum, School of Dentistry, University of Buenos Aires, C1053ABJ Buenos Aires, Argentina.
Servicio Geológico Minero Argentino · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori (H. pylori) has been found in the oral cavity and stomach, and its infection is one of the most frequent worldwide. We reviewed the literature and conducted a Topic Highlight, which identified studies reporting an association between H. pylori-infection in the oral cavity and H. pylori-positive stomach bacterium. This work was designed to determine whether H. pylori is the etiologic agent in periodontal disease, recurrent aphthous stomatitis (RAS), squamous cell carcinoma, burning and halitosis. Record selection focused on the highest quality studies and meta-analyses. We selected 48 articles reporting on the association between saliva and plaque and H. pylori-infection. In order to assess periodontal disease data, we included 12 clinical trials and 1 meta-analysis. We evaluated 13 published articles that addressed the potential association with RAS, and 6 with squamous cell carcinoma. Fourteen publications focused on our questions on burning and halitosis. There is a close relation between H. pylori infection in the oral cavity and the stomach. The mouth is the first extra-gastric reservoir. Regarding the role of H. pylori in the etiology of squamous cell carcinoma, no evidence is still available.

Indexed as

Dental PlaqueGastritisHelicobacter InfectionsHelicobacter pyloriHumansMouthMouth DiseasesPrognosisRisk FactorsSalivaStomachBurning and halitosisGastric infectionHelicobacter pyloriOral pathologyRecurrent aphthous stomatitis

Identifiers

PMID25110422
PMCPMC4123373
OpenAlexW1999572925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.