Evidence map›Paper›PMID 25110394›Full record

ArticleJournal of applied phycology2014

Evolution of acyl-ACP-thioesterases and β-ketoacyl-ACP-synthases revealed by protein-protein interactions.

Joris Beld, Jillian L Blatti, Craig Behnke, Michael Mendez, Michael D Burkart

Open access · greenAbstract read
In one paragraph

Article in Journal of applied phycology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.Clinical nutrition (Edinburgh, Scotland) · 2022
    Trial
  4. Article
  5. Review
  6. Novel Targets for Antimicrobials.Turkish journal of pharmaceutical sciences · 2020
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Using modern tools to probe the structure-function relationship of fatty acid synthases.Chembiochem : a European journal of chemical biology · 2015
    Review
  12. Review
  13. Visualizing the chain-flipping mechanism in fatty-acid biosynthesis.Angewandte Chemie (International ed. in English) · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Joris BeldDepartment of Chemistry and Biochemistry, University of California-San Diego, La Jolla, CA 92093-0358, USA.
Jillian L BlattiDepartment of Chemistry and Biochemistry, University of California-San Diego, La Jolla, CA 92093-0358, USA.
Craig BehnkeDepartment of Chemistry and Biochemistry, University of California-San Diego, La Jolla, CA 92093-0358, USA.
Michael MendezDepartment of Chemistry and Biochemistry, University of California-San Diego, La Jolla, CA 92093-0358, USA.
Michael D BurkartDepartment of Chemistry and Biochemistry, University of California-San Diego, La Jolla, CA 92093-0358, USA.
University of California, San Diego · US

Funding

Protein-Protein Interactions in Natural Product BiosynthesisR01GM095970 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BURKART, MICHAEL D. · 2012 to 2025
$5.9M
OASIS to identify and analyze natural product biosynthesisR01GM094924 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BURKART, MICHAEL D. · 2010 to 2013
$1.2M
NIGMS NIH HHS R01 GM094924NIGMS NIH HHS R01 GM095970
6 · The paper itself

Abstract

The fatty acid synthase (FAS) is a conserved primary metabolic enzyme complex capable of tolerating cross-species engineering of domains for the development of modified and overproduced fatty acids. In eukaryotes, acyl-acyl carrier protein thioesterases (TEs) off-load mature cargo from the acyl carrier protein (ACP), and plants have developed TEs for short/medium-chain fatty acids. We showed that engineering plant TEs into the green microalga

Indexed as

acyl carrier proteinalgaebacteriaChlamydomonas reinhardtiievolutionfatty acid synthase

Identifiers

PMID25110394
PMCPMC4125210
OpenAlexW2086338765

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.