Evidence map›Paper›PMID 25110033›Full record

ReviewBiochemical Society transactions2014

Current perspectives on RNA secondary structure probing.

Julia Kenyon, Liam Prestwood, Andrew Lever

Abstract readReview
In one paragraph

Review in Biochemical Society transactions, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Small molecule approaches to targeting RNA.Nature reviews. Chemistry · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julia Kenyon*University of Cambridge Department of Medicine, Box 157 Level 5 Addenbrooke's Hospital, Hills Road, Cambridge, Cambridgeshire CB2 0QQ, U.K.
Liam Prestwood*University of Cambridge Department of Medicine, Box 157 Level 5 Addenbrooke's Hospital, Hills Road, Cambridge, Cambridgeshire CB2 0QQ, U.K.
Andrew Lever*University of Cambridge Department of Medicine, Box 157 Level 5 Addenbrooke's Hospital, Hills Road, Cambridge, Cambridgeshire CB2 0QQ, U.K.

Funding

Medical Research Council G0800142Medical Research Council G0801709Wellcome Trust 078007/Z/05/Z
6 · The paper itself

Abstract

The range of roles played by structured RNAs in biological systems is vast. At the same time as we are learning more about the importance of RNA structure, recent advances in reagents, methods and technology mean that RNA secondary structural probing has become faster and more accurate. As a result, the capabilities of laboratories that already perform this type of structural analysis have increased greatly, and it has also become more widely accessible. The present review summarizes established and recently developed techniques. The information we can derive from secondary structural analysis is assessed, together with the areas in which we are likely to see exciting developments in the near future.

Indexed as

AlgorithmsAnimalsComputational BiologyHumansNucleic Acid ConformationProtein Structure, SecondaryRNARNA

Identifiers

PMID25110033
PMCPMC4128643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.