ReviewThe Indian journal of medical research2014
Prevention of ventilator-associated pneumonia in the intensive care unit: a review of the clinically relevant recent advancements.
Review in The Indian journal of medical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.
- Systematic review of studies investigating ventilator associated pneumonia diagnostics in intensive care.BMC pulmonary medicine · 2021Pooled it
- Oral Hygiene Interventions and Pneumonia Prevention in Critical Care: An Integrative Review of Evidence and Practice.International journal of dentistry · 2026Review
- Predictors of ventilator-associated pneumonia in intubated pediatric trauma patients.Pediatric surgery international · 2025Article
- Whole genome comparisons reveal gut-to-lung translocation of Escherichia coli and Burkholderia cenocepacia in two cases of ventilator-associated pneumonia in ICU patients.Respiratory research · 2025Article
- Ventilator-associated pneumonia - What price does the public health system pay?Lung India : official organ of Indian Chest Society · 2024Article
- Reviving Hope: A Comprehensive Review of Post-resuscitation Care in Pediatric ICUs After Cardiac Arrest.Cureus · 2023Review
- Effect of COVID-19 pneumonia infection control protocols on nosocomial infection incidence in trauma patients.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2023Article
- Approaches for Mitigating Microbial Biofilm-Related Drug Resistance: A Focus on Micro- and Nanotechnologies.Molecules (Basel, Switzerland) · 2021Review
- Knowledge, attitude, and expertise of nurses in intensive care unit regarding oral and dental care in hospitalized patients.Dental research journal · 2021Article
- The Impact of COVID-19 Outbreak on Nosocomial Infection Rate: A Case of Iran.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2021Article
- Assessment of post-trauma complications in eight million trauma cases over a decade in the USA.Trauma surgery & acute care open · 2021Article
- Care bundles for improving outcomes in patients with COVID-19 or related conditions in intensive care - a rapid scoping review.The Cochrane database of systematic reviews · 2020Article
- Impact of Oral Care and Antisepsis on the Prevalence of Ventilator-Associated Pneumonia.Oral health & preventive dentistry · 2020Article
- Risk Factors of Pneumonia Associated with Mechanical Ventilation.International journal of environmental research and public health · 2020Article
- The Effects of Open and Closed Suction Methods on Occurrence of Ventilator Associated Pneumonia; a Comparative Study.Archives of academic emergency medicine · 2020Article
- Muscle weakness associated with H7N9 infection: report of two cases.BMC infectious diseases · 2018Article
- Microbiological monitoring of continuous positive airway pressure and resuscitation equipment in very-low birth weight infants.Pediatric research · 2018Article
- Zinc Supplementation in Adult Mechanically Ventilated Trauma Patients is Associated with Decreased Occurrence of Ventilator-associated Pneumonia: A Secondary Analysis of a Prospective, Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2017Article
- Article
- Authors' response.The Indian journal of medical research · 2015Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
Ventilator-associated pneumonia (VAP) is one of the most commonly encountered hospital-acquired infections in intensive care units and is associated with significant morbidity and high costs of care. The pathophysiology, epidemiology, treatment and prevention of VAP have been extensively studied for decades, but a clear prevention strategy has not yet emerged. In this article we will review recent literature pertaining to evidence-based VAP-prevention strategies that have resulted in clinically relevant outcomes. A multidisciplinary strategy for prevention of VAP is recommended. Those interventions that have been shown to have a clinical impact include the following: (i) Non-invasive positive pressure ventilation for able patients, especially in immunocompromised patients, with acute exacerbation of chronic obstructive pulmonary disease or pulmonary oedema, (ii) Sedation and weaning protocols for those patients who do require mechanical ventilation, (iii) Mechanical ventilation protocols including head of bed elevation above 30 degrees and oral care, and (iv) Removal of subglottic secretions. Other interventions, such as selective digestive tract decontamination, selective oropharyngeal decontamination and antimicrobial-coated endotracheal tubes, have been tested in different studies. However, the evidence for the efficacy of these measures to reduce VAP rates is not strong enough to recommend their use in clinical practice. In numerous studies, the implementation of VAP prevention bundles to clinical practice was associated with a significant reduction in VAP rates. Future research that considers clinical outcomes as primary endpoints will hopefully result in more detailed prevention strategies.
Indexed as
Identifiers
25109715PMC4164993W1613155499What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.