Evidence map›Paper›PMID 25108382›Full record

ArticleVirology2014

Novel flaviviruses from mosquitoes: mosquito-specific evolutionary lineages within the phylogenetic group of mosquito-borne flaviviruses.

Eili Huhtamo, Shelley Cook, Gregory Moureau, Nathalie Y Uzcátegui, Tarja Sironen, Suvi Kuivanen, Niina Putkuri, Satu Kurkela, Ralph E Harbach, Andrew E Firth and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. Pooled it
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  13. Replication is the key barrier during the dual-host adaptation of mosquito-borne flaviviruses.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  14. Article
  15. Dissecting the Species-Specific Virome inFrontiers in microbiology · 2022
    Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Eili HuhtamoDepartment of Virology, Haartman Institute, Faculty of Medicine, University of Helsinki, Helsinki, Finland. Electronic address: eili.huhtamo@helsinki.fi.
Shelley CookDepartment of Life Sciences, Natural History Museum, Cromwell Road, London SW7 5BD, United Kingdom.
Gregory MoureauUMR D 190 "Emergence des Pathologies Virales", Aix Marseille University, IRD French Institute of Research for Development, EHESP French School of Public Health, 27 Boulevard Jean Moulin, Marseille 13005, France.
Nathalie Y UzcáteguiDepartment of Virology, Haartman Institute, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Tarja SironenDepartment of Virology, Haartman Institute, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Suvi KuivanenDepartment of Virology, Haartman Institute, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Niina PutkuriDepartment of Virology, Haartman Institute, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Satu KurkelaDepartment of Virology, Haartman Institute, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Department of Virology and Immunology, Helsinki University Central Hospital Laboratory (HUSLAB), P.O. Box 400, Haartmaninkatu 3, 00029 HUS, Helsinki, Finland.
Ralph E HarbachDepartment of Life Sciences, Natural History Museum, Cromwell Road, London SW7 5BD, United Kingdom.
Andrew E FirthDivision of Virology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom.
Olli VapalahtiDepartment of Virology, Haartman Institute, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Department of Virology and Immunology, Helsinki University Central Hospital Laboratory (HUSLAB), P.O. Box 400, Haartmaninkatu 3, 00029 HUS, Helsinki, Finland; Division of Microbiology and Epidemiology, Department of Basic Veterinary Sciences, University of Helsinki, Helsinki, Finland.
Ernest A GouldUMR D 190 "Emergence des Pathologies Virales", Aix Marseille University, IRD French Institute of Research for Development, EHESP French School of Public Health, 27 Boulevard Jean Moulin, Marseille 13005, France.
Xavier de LamballerieUMR D 190 "Emergence des Pathologies Virales", Aix Marseille University, IRD French Institute of Research for Development, EHESP French School of Public Health, 27 Boulevard Jean Moulin, Marseille 13005, France.
University of Helsinki · FIÉcole des Hautes Études en Santé Publique · FRNatural History Museum · GBUniversity of Cambridge · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Novel flaviviruses that are genetically related to pathogenic mosquito-borne flaviviruses (MBFV) have been isolated from mosquitoes in various geographical locations, including Finland. We isolated and characterized another novel virus of this group from Finnish mosquitoes collected in 2007, designated as Ilomantsi virus (ILOV). Unlike the MBFV that infect both vertebrates and mosquitoes, the MBFV-related viruses appear to be specific to mosquitoes similar to the insect-specific flaviviruses (ISFs). In this overview of MBFV-related viruses we conclude that they differ from the ISFs genetically and antigenically. Phylogenetic analyses separated the MBFV-related viruses isolated in Africa, the Middle East and South America from those isolated in Europe and Asia. Serological cross-reactions of MBFV-related viruses with other flaviviruses and their potential for vector-borne transmission require further characterization. The divergent MBFV-related viruses are probably significantly under sampled to date and provide new information on the variety, properties and evolution of vector-borne flaviviruses.

Indexed as

Evolution, MolecularPhylogenyAfricaAnimalsBase SequenceCulicidaeFemaleFlavivirusFlavivirus InfectionsHumansInsect VectorsMaleMolecular Sequence DataComplete genomeFlavivirusIsolateMosquitoPhylogenetic analysis

Identifiers

PMID25108382
PMCPMC4170750
OpenAlexW2079706267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.