ArticleApplied and environmental microbiology2014
Two novel toxin variants revealed by whole-genome sequencing of 175 Clostridium botulinum type E strains.
Article in Applied and environmental microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guideline
- Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.Nature communications · 2023Article
- Pan-Genomic Analysis ofToxins · 2020Article
- Variations in the Botulinum Neurotoxin Binding Domain and the Potential for Novel Therapeutics.Toxins · 2018Review
- A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes.Toxins · 2018Article
- Impact ofCurrent opinion in food science · 2016Review
- Diversity of Group I and II Clostridium botulinum Strains from France Including Recently Identified Subtypes.Genome biology and evolution · 2016Article
- Comparative genomic analyses reveal broad diversity in botulinum-toxin-producing Clostridia.BMC genomics · 2016Article
- Evolution of Chromosomal Clostridium botulinum Type E Neurotoxin Gene Clusters: Evidence Provided by Their Rare Plasmid-Borne Counterparts.Genome biology and evolution · 2016Article
- New Elements To Consider When Modeling the Hazards Associated with Botulinum Neurotoxin in Food.Journal of bacteriology · 2016Review
- Clostridium botulinum Group II Isolate Phylogenomic Profiling Using Whole-Genome Sequence Data.Applied and environmental microbiology · 2015Article
- An atypical outbreak of food-borne botulism due to Clostridium botulinum types B and E from ham.Journal of clinical microbiology · 2015Article
- Isolation and functional characterization of the novel Clostridium botulinum neurotoxin A8 subtype.PloS one · 2015Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We sequenced 175 Clostridium botulinum type E strains isolated from food, clinical, and environmental sources from northern Canada and analyzed their botulinum neurotoxin (bont) coding sequences (CDSs). In addition to bont/E1 and bont/E3 variant types, neurotoxin sequence analysis identified two novel BoNT type E variants termed E10 and E11. Strains producing type E10 were found along the eastern coastlines of Hudson Bay and the shores of Ungava Bay, while strains producing type E11 were only found in the Koksoak River region of Nunavik. Strains producing BoNT/E3 were widespread throughout northern Canada, with the exception of the coast of eastern Hudson Bay.
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